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Details

Stereochemistry ACHIRAL
Molecular Formula 5S.2Sb
Molecular Weight 403.845
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -10

SHOW SMILES / InChI
Structure of ANTIMONY PENTASULFIDE

SMILES

[S--].[S--].[S--].[S--].[S--].[SbH3].[SbH3]

InChI

InChIKey=DQQPIVPONBAHNF-UHFFFAOYSA-N
InChI=1S/5S.2Sb.6H/q5*-2;;;;;;;;

HIDE SMILES / InChI
Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Sb
Molecular Weight 121.76
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Originator

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
ATP-dependent 6-phosphofructokinase
21
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8429
Fuadin

Approved Use

Schistosomiasis
PubMed

PubMed

TitleDatePubMed
Patents

Patents

03976788
20
04062962
20
04197262
20
04562009
22
04596784
20
05025031
25
05463088
20
05656573
25
05776425
20
07713950
20
07737233
22
08268997
20
08354532
21
20080146527
20
20090076227
20
20090124802
20
7361689
20
7615300
20
US3085943
20
US3965016
20
US5232441
21

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:38:21 UTC 2023
Edited
by admin
on Fri Dec 15 16:38:21 UTC 2023
Record UNII
1433F1I86N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY PENTASULFIDE
MART.   MI   WHO-DD  
Common Name English
ANTIMONY SULFIDE (SB2S5)
Common Name English
ANTIMONY PENTASULFIDE [MI]
Common Name English
ANTIMONIUM SULPHURATUM AUREUM
HPUS  
Common Name English
DIANTIMONY PENTASULPHIDE
Common Name English
GOLDEN ANTIMONY SULPHIDE
Common Name English
ANTIMONIC SULFIDE
Common Name English
ANTIMONY PENTASULPHIDE
Common Name English
GOLDEN ANTIMONY SULFIDE
Common Name English
ANTIMONIUM SULPHURATUM AUREUM [HPUS]
Common Name English
Antimony pentasulfide [WHO-DD]
Common Name English
ANTIMONY SULFIDE
Systematic Name English
ANTIMONIC SULPHIDE
Common Name English
ANTIMONY SULPHIDE (SB2S5)
Common Name English
ANTIMONY PENTASULFIDE [MART.]
Common Name English
ANTIMONY SULPHIDE
Systematic Name English
Classification Tree Code System Code
WHO-ATC R05CA07
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
WHO-VATC QR05CA07
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
Code System Code Type Description
MERCK INDEX
m1958
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY Merck Index
CAS
1315-04-4
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
PUBCHEM
90478371
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
SMS_ID
100000183864
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
ChEMBL
CHEMBL3707259
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
RXCUI
1337969
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY RxNorm
DRUG CENTRAL
4838
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
WIKIPEDIA
ANTIMONY PENTASULFIDE
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
ECHA (EC/EINECS)
215-255-5
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
DRUG BANK
DB13473
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
DAILYMED
1433F1I86N
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
EPA CompTox
DTXSID8046583
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
MESH
C060390
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
FDA UNII
1433F1I86N
Created by admin on Fri Dec 15 16:38:22 UTC 2023 , Edited by admin on Fri Dec 15 16:38:22 UTC 2023
PRIMARY
Related Record Type Details
Structure of ANTIMONY CATION (5+)
PARENT -> SALT/SOLVATE
Structure of HYDROGEN SULFIDE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of ANTIMONY PENTASULFIDE
ACTIVE MOIETY
NIH
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