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Details

Stereochemistry ACHIRAL
Molecular Formula Sb
Molecular Weight 121.76
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 5

SHOW SMILES / InChI
Structure of ANTIMONY CATION (5+)

SMILES

[Sb+5]

InChI

InChIKey=ZDINGUUTWDGGFF-UHFFFAOYSA-N
InChI=1S/Sb/q+5

HIDE SMILES / InChI
Molecular Formula Sb
Molecular Weight 121.76
Charge 5
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Originator

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
ATP-dependent 6-phosphofructokinase
21
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8429
Fuadin

Approved Use

Schistosomiasis
PubMed

PubMed

TitleDatePubMed
Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes.
2012 Jul
Patents

Patents

03976788
20
04062962
20
04197262
20
04562009
22
04596784
20
05025031
25
05463088
20
05656573
25
05776425
20
07713950
20
07737233
22
08268997
20
08354532
21
20080146527
20
20090076227
20
20090124802
20
7361689
20
7615300
20
US3085943
20
US3965016
20
US5232441
21

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:41:30 GMT 2023
Edited
by admin
on Fri Dec 15 16:41:30 GMT 2023
Record UNII
841L03HG64
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY CATION (5+)
Common Name English
ANTIMONY(5+)
Systematic Name English
ANTIMONY, ION (SB5+)
Common Name English
PENTAVALENT ANTIMONY
Common Name English
SB5+
Common Name English
Code System Code Type Description
PUBCHEM
73608879
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY PUBCHEM
FDA UNII
841L03HG64
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY
CAS
22537-51-5
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY
RXCUI
1546283
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY RxNorm
EPA CompTox
DTXSID50872431
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY
DRUG BANK
DB13047
Created by admin on Fri Dec 15 16:41:30 GMT 2023 , Edited by admin on Fri Dec 15 16:41:30 GMT 2023
PRIMARY
Related Record Type Details
Structure of ANTIMONY CATION (5+)
IONIC MOIETY
Structure of ANTIMONY PENTASULFIDE
SALT/SOLVATE -> PARENT
Structure of ANTIMONY PENTACHLORIDE
SALT/SOLVATE -> PARENT
NIH
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