SODIUM BISULFIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	Na.HS
Molecular Weight	56.063
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[SH-]

InChI

InChIKey=HYHCSLBZRBJJCH-UHFFFAOYSA-M

InChI=1S/Na.H2S/h;1H2/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	H2S
Molecular Weight	34.081
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Hydrogen sulfide (H2S) attenuates uranium-induced acute nephrotoxicity through oxidative stress and inflammatory response via Nrf2-NF-κB pathways.	2015-12-05	26523793
Dexamethasone ameliorates H₂S-induced acute lung injury by alleviating matrix metalloproteinase-2 and -9 expression.	2014	24722316
Inhibition of ROS-activated p38MAPK pathway is involved in the protective effect of H2S against chemical hypoxia-induced inflammation in PC12 cells.	2013-07	23624824
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells.	2013-07	23479079
Hydrogen sulfide protects SH-SY5Y neuronal cells against d-galactose induced cell injury by suppression of advanced glycation end products formation and oxidative stress.	2013-04	23274001
Hydrogen sulfide protects PC12 cells against reactive oxygen species and extracellular signal-regulated kinase 1/2-mediated downregulation of glutamate transporter-1 expression induced by chemical hypoxia.	2012-11	22895544
Combined effects of hydrogen sulfide and lipopolysaccharide on osteoclast differentiation in rats.	2012-04	21910595
Inhibition of ROS-activated ERK1/2 pathway contributes to the protection of H2S against chemical hypoxia-induced injury in H9c2 cells.	2012-03	22134701
Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells.	2011-12-15	22005276
Hydrogen sulfide regulates vascular endoplasmic reticulum stress in apolipoprotein E knockout mice.	2011-11	22340159
Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model.	2011	22046339
Hydrogen sulfide protects against chemical hypoxia-induced injury by inhibiting ROS-activated ERK1/2 and p38MAPK signaling pathways in PC12 cells.	2011	21998720
Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway.	2011	21779360
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.	2008-02	18031925
The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase.	2003-10	14508194

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:04:03 GMT 2025` Edited by `admin` on `Mon Mar 31 18:04:03 GMT 2025`
Record UNII	FWU2KQ177W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM BISULFIDE

Common Name

English

SODIUM HYDROSULFIDE

Preferred Name

English

NA2922

Code

English

SODIUM BISULFIDE [MI]

Common Name

English

NSC-158264

Code

English

SODIUM HYDROSULPHIDE SOLUTION

Common Name

English

SODIUM BISULPHIDE

Common Name

English

SODIUM HYDROSULPHIDE

Systematic Name

English

SODIUM HYDROSULFIDE [HSDB]

Common Name

English

SODIUM HYDROSULFIDE SOLUTION

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C77495