U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.S.5H2O
Molecular Weight 168.121
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM SULFIDE PENTAHYDRATE

SMILES

O.O.O.O.O.[Na+].[Na+].[S--]

InChI

InChIKey=XWKIXFQOFAVHQI-UHFFFAOYSA-N
InChI=1S/2Na.5H2O.S/h;;5*1H2;/q2*+1;;;;;;-2

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

A sulfide ion is composed of a lone sulfur atom. Its charge is negative two, giving sulfides this formula: S^2-. Sulfide is a strong base, so solutions of sulfide in water are basic, due to hydrolysis. One well-known ionic compound with a sulfide ion is H_2S. The infamous rotten-egg smell often associated with sulfur originates from this compound. Sodium sulfide nonahydrate is used in the formation of surface functionalized cadmium sulfide quantum dots.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
DR. SCHOLLS INGROWN TOENAIL PAIN RELIEVER

Approved Use

Use: - For temporary relief of pain and discomfort from ingrown toenails.

Launch Date

2003
PubMed

PubMed

TitleDatePubMed
Clinical comparison of two radiocolloids for internal mammary lymphoscintigraphy.
1985 Dec
Lung dysfunction in animal confinement workers--chairman's report to the Scientific Committee of the Third International Symposium: issues in health, safety and agriculture, held in Saskatoon, Saskatchewan, Canada, May 10-15, 1992.
1992
Chemosensory event-related potentials in the investigation of interactions between the olfactory and the somatosensory (trigeminal) systems.
1992 Sep
The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases.
1997
A fatal case of hydrogen sulfide poisoning in a geothermal power plant.
1998 Jul
HG/LT-GC/ICP-MS coupling for identification of metal(loid) species in human urine after fish consumption.
2001 Nov
Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.
2002
Fatal and nonfatal poisoning by hydrogen sulfide at an industrial waste site.
2002 May
Novel neural modulators.
2003
A salivary incubation test for evaluation of oral malodor: a pilot study.
2003 Jul
Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine.
2004 Dec 10
Major and trace elements in whole blood of phlebotomized patients with porphyria cutanea tarda.
2005
Biochemical differentiation and comparison of Desulfovibrio species and other phenotypically similar genera.
2005 Aug
Induction of phase I, II and III drug metabolism/transport by xenobiotics.
2005 Mar
The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis.
2005 Sep
Emergency room visits for respiratory conditions in children increased after Guagua Pichincha volcanic eruptions in April 2000 in Quito, Ecuador observational study: time series analysis.
2007 Jul 24
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
2008 Feb
Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery.
2008 Feb
Disulfides as cyanide antidotes: evidence for a new in vivo oxidative pathway for cyanide detoxification.
2009 Dec
Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury.
2009 Mar
Time-series analysis of mortality effects of fine particulate matter components in Detroit and Seattle.
2011 Apr
S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.
2011 Jun
Detoxification of methylmercury by hydrogen sulfide-producing enzyme in Mammalian cells.
2011 Oct 17
A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide.
2013
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells.
2013 Jul
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:02:36 GMT 2023
Edited
by admin
on Fri Dec 15 17:02:36 GMT 2023
Record UNII
6U55N59SZ2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM SULFIDE PENTAHYDRATE
MI  
Common Name English
SODIUM MONOSULPHIDE PENTAHYDRATE
Common Name English
SODIUM SULPHIDE PENTAHYDRATE
Common Name English
SODIUM SULFIDE PENTAHYDRATE [MI]
Common Name English
SODIUM MONOSULFIDE PENTAHYDRATE
Common Name English
Code System Code Type Description
FDA UNII
6U55N59SZ2
Created by admin on Fri Dec 15 17:02:36 GMT 2023 , Edited by admin on Fri Dec 15 17:02:36 GMT 2023
PRIMARY
MERCK INDEX
m10080
Created by admin on Fri Dec 15 17:02:36 GMT 2023 , Edited by admin on Fri Dec 15 17:02:36 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID60156996
Created by admin on Fri Dec 15 17:02:36 GMT 2023 , Edited by admin on Fri Dec 15 17:02:36 GMT 2023
PRIMARY
CAS
1313-83-3
Created by admin on Fri Dec 15 17:02:36 GMT 2023 , Edited by admin on Fri Dec 15 17:02:36 GMT 2023
PRIMARY
PUBCHEM
20129742
Created by admin on Fri Dec 15 17:02:36 GMT 2023 , Edited by admin on Fri Dec 15 17:02:36 GMT 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY