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Details

Stereochemistry ACHIRAL
Molecular Formula S
Molecular Weight 32.065
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of SULFIDE ION

SMILES

[S--]

InChI

InChIKey=UCKMPCXJQFINFW-UHFFFAOYSA-N
InChI=1S/S/q-2

HIDE SMILES / InChI

Molecular Formula H2S
Molecular Weight 34.081
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

A sulfide ion is composed of a lone sulfur atom. Its charge is negative two, giving sulfides this formula: S^2-. Sulfide is a strong base, so solutions of sulfide in water are basic, due to hydrolysis. One well-known ionic compound with a sulfide ion is H_2S. The infamous rotten-egg smell often associated with sulfur originates from this compound. Sodium sulfide nonahydrate is used in the formation of surface functionalized cadmium sulfide quantum dots.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
DR. SCHOLLS INGROWN TOENAIL PAIN RELIEVER

Approved Use

Use: - For temporary relief of pain and discomfort from ingrown toenails.

Launch Date

2003
PubMed

PubMed

TitleDatePubMed
Convulsions following application of gamma benzene hexachloride.
1981 Jul
Clinical comparison of two radiocolloids for internal mammary lymphoscintigraphy.
1985 Dec
Widespread occurrence of bacterial thiol methyltransferases and the biogenic emission of methylated sulfur gases.
1987 Jul
Activity of polymorphonuclear leukocytes in the presence of sulfide.
1989 Sep
Lung dysfunction in animal confinement workers--chairman's report to the Scientific Committee of the Third International Symposium: issues in health, safety and agriculture, held in Saskatoon, Saskatchewan, Canada, May 10-15, 1992.
1992
Chemosensory event-related potentials in the investigation of interactions between the olfactory and the somatosensory (trigeminal) systems.
1992 Sep
The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases.
1997
A fatal case of hydrogen sulfide poisoning in a geothermal power plant.
1998 Jul
Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis.
2001 Aug
Gas production by feces of infants.
2001 May
HG/LT-GC/ICP-MS coupling for identification of metal(loid) species in human urine after fish consumption.
2001 Nov
Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE.
2002
Fatal and nonfatal poisoning by hydrogen sulfide at an industrial waste site.
2002 May
Novel neural modulators.
2003
A salivary incubation test for evaluation of oral malodor: a pilot study.
2003 Jul
Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine.
2004 Dec 10
Major and trace elements in whole blood of phlebotomized patients with porphyria cutanea tarda.
2005
Biochemical differentiation and comparison of Desulfovibrio species and other phenotypically similar genera.
2005 Aug
Induction of phase I, II and III drug metabolism/transport by xenobiotics.
2005 Mar
The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis.
2005 Sep
Emergency room visits for respiratory conditions in children increased after Guagua Pichincha volcanic eruptions in April 2000 in Quito, Ecuador observational study: time series analysis.
2007 Jul 24
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
2008 Feb
Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery.
2008 Feb
Disulfides as cyanide antidotes: evidence for a new in vivo oxidative pathway for cyanide detoxification.
2009 Dec
Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury.
2009 Mar
HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans.
2011
Time-series analysis of mortality effects of fine particulate matter components in Detroit and Seattle.
2011 Apr
S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.
2011 Jun
Detoxification of methylmercury by hydrogen sulfide-producing enzyme in Mammalian cells.
2011 Oct 17
Indoor air pollutants and health in the United Arab Emirates.
2012 May
A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide.
2013
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells.
2013 Jul
Dexamethasone ameliorates H₂S-induced acute lung injury by alleviating matrix metalloproteinase-2 and -9 expression.
2014
Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.
2014 Aug 22
H2S inhibition of chemical hypoxia-induced proliferation of HPASMCs is mediated by the upregulation of COX-2/PGI2.
2014 Feb
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:42:43 GMT 2023
Edited
by admin
on Sat Dec 16 01:42:43 GMT 2023
Record UNII
G15I91XETI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SULFIDE ION
Common Name English
SULFUR, ION (S2-)
Common Name English
SULPHIDE
Common Name English
SULFIDE
Common Name English
SULPHIDE ION
Common Name English
Code System Code Type Description
DAILYMED
G15I91XETI
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
RXCUI
1368379
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY RxNorm
CHEBI
15138
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
SMS_ID
100000126196
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
CHEBI
16136
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
EPA CompTox
DTXSID20872928
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
CHEBI
16385
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
WIKIPEDIA
SULFIDE
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
CAS
18496-25-8
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
PUBCHEM
29109
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
EVMPD
SUB32976
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
FDA UNII
G15I91XETI
Created by admin on Sat Dec 16 01:42:43 GMT 2023 , Edited by admin on Sat Dec 16 01:42:43 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY