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Details

Stereochemistry ACHIRAL
Molecular Formula Co.S
Molecular Weight 90.998
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COBALTOUS SULFIDE

SMILES

[S--].[Co++]

InChI

InChIKey=INPLXZPZQSLHBR-UHFFFAOYSA-N
InChI=1S/Co.S/q+2;-2

HIDE SMILES / InChI

Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Co
Molecular Weight 58.933195
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cobalt is a transition metal, naturally ocurring in the minerals cobaltite, smaltite, and erythrite, and is often associated with nickel, silver, lead, copper, and iron ores, from which it is most frequently obtained as a by-product. Depending on the considered species, cobalt has multiple industrial applications including the production of alloys and hard metal, diamond polishing, drying agents, pigments and catalysts. Cobalt is an essential component of Vitamin B12 (hydroxycolalamin). Cobalt functions as a co-factor in enzyme catalysed reactions and is involved in the production of erythropoietin, a hormone that stimulates the formation of erythrocytes. Cobalt salts were used to treat anemia and stimulate erythropoiesis, but was withdrawn from market since Co(II) cations are genotoxic in vitro and in vivo, and carcinogenic in rodents. Hovewer, Co salts are reported to be used by athletes as a doping

Originator

Curator's Comment: Cobalt was discovered by Georg Brandt, a Swedish chemist, in 1739.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q9NWT6
Gene ID: 55662.0
Gene Symbol: HIF1AN
Target Organism: Homo sapiens (Human)
1.0 µM [Ki]
Conditions
PubMed

PubMed

TitleDatePubMed
Acute oral toxicity of inorganic cobalt compounds in rats.
1982 Jun
Synthesis and Anti-Candida Activity of Cobalt(II) Complexes of Benzene-1,2-Dioxyacetic Acid (bdoaH(2)). X-Ray Crystal Structures of [Co(bdoa)(H(2)O)(3)] 3.5H(2)O and {[CO(phen)(3)](bdoa)}(2)24H(2)O (phen = 1,10-Phenanthroline).
1999
Determination of trace metal ions in common salt by stripping voltammetry.
1999 Nov-Dec
Cobalt and antimony: genotoxicity and carcinogenicity.
2003 Dec 10
Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals.
2009 Apr
Purification and characterization of glucose 6-phosphate dehydrogenase enzyme from rainbow trout (Oncorhynchus mykiss) liver and investigation of the effects of some metal ions on enzyme activity.
2015 May
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:53:02 GMT 2025
Edited
by admin
on Mon Mar 31 19:53:02 GMT 2025
Record UNII
INZ5E36Y1V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
COBALT MONOSULFIDE
HSDB  
Preferred Name English
COBALTOUS SULFIDE
MI  
Common Name English
COBALTOUS SULFIDE [MI]
Common Name English
COBALT SULPHIDE
Systematic Name English
COBALT MONOSULFIDE [HSDB]
Common Name English
COBALT(II) SULFIDE
Systematic Name English
COBALT SULFIDE
Systematic Name English
Code System Code Type Description
MERCK INDEX
m3703
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY Merck Index
FDA UNII
INZ5E36Y1V
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
WIKIPEDIA
COBALT SULFIDE
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
CAS
1317-42-6
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
215-273-3
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
SMS_ID
300000053137
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
PUBCHEM
159453
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
MESH
C027875
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
HSDB
5448
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
EPA CompTox
DTXSID80892187
Created by admin on Mon Mar 31 19:53:02 GMT 2025 , Edited by admin on Mon Mar 31 19:53:02 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE