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Details

Stereochemistry ACHIRAL
Molecular Formula Co
Molecular Weight 58.9332
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of COBALTOUS CATION

SMILES

[Co++]

InChI

InChIKey=XLJKHNWPARRRJB-UHFFFAOYSA-N
InChI=1S/Co/q+2

HIDE SMILES / InChI
Molecular Formula Co
Molecular Weight 58.9332
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/104729ISBN 9780873715980, Foden C.R., Weddell J.L., 'Hazardous Materials: Emergency Action Data' (1991), Retrieved from https://books.google.com/books?id=4IPE8Pjhm8UC&pgISBN: 978-94-010-7024-9, Matar M.S., Mirbach M.J.,Tayim H.A. 'Catalysis in Petrochemical Processes' (1988), p.136, Retrieved from https://books.google.com/books?id=MkD2JnDkZYYC&dqhttp://aygrt.isrj.org/colorArticles/4972.pdfhttp://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb744048e0023/pdfhttps://www.ncbi.nlm.nih.gov/pubmed/27527840https://fscimage.fishersci.com/msds/05330.htmhttp://laboratorychemicals.in/uploads/msds/10026-17-2-49128.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/2253206https://monographs.iarc.fr/ENG/Monographs/vol52/mono52-16.pdfhttp://datasheets.scbt.com/sc-227251.pdf
Curator's Comment: description was created based on several sources, including: DOI:10.1080/00958970802416020 | DOI:10.1080/00958972.2010.521553 | https://www.ncbi.nlm.nih.gov/pubmed/7201957 | https://www.ncbi.nlm.nih.gov/pubmed/18475879

Cobaltous iodide is a catalyst used in organic synthesis.

Originator

Brandt, G.
20
Curator's Comment: Cobalt was discovered by Georg Brandt, a Swedish chemist, in 1739.

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
Hypoxia-inducible factor 1-alpha inhibitor
22
Target ID: Q9NWT6
Gene ID: 55662.0
Gene Symbol: HIF1AN
Target Organism: Homo sapiens (Human)
Inhibitor
8297
 1.0 µM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Withdrawn
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Synthesis and antifungal potential of Co(II) complexes of 1-(2'-hydroxyphenyl) ethylideneanilines.
2006 Feb
Patents

Patents

US20150010463
20
US3459677 A
20
US4326084
20
US5718844
20
US6740618 B2
20
WO2014127808A1
20

Sample Use Guides

In Vivo Use Guide
For treatment of anemia, oral cobal chloride was administered at doses 25 mg and 50 mg daily.
Route of Administration: Oral
In Vitro Use Guide
HIF asparaginyl hydroxylase activity was measured by a method based on the hydroxylation coupled decarboxylation of 2-oxoglutarate with the synthetic HIF-1α peptides in the presence of varying concentrations of Co (1-5 uM). Ki for HIF asparaginyl hydroxylase was 1uM.
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:48:34 GMT 2023
Edited
by admin
on Fri Dec 15 18:48:34 GMT 2023
Record UNII
AI1MR454XG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
COBALTOUS CATION
Common Name English
CO2+
Common Name English
COBALT(II) CATION
Common Name English
COBALT CATION (CO2+)
Common Name English
COBALT(II) ION
Common Name English
COBALTOUS ION
Common Name English
COBALT, ION (CO2+)
Common Name English
COBALT(2+)
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C68247
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID20177066
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
DAILYMED
AI1MR454XG
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
NCI_THESAURUS
C68248
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
CAS
22541-53-3
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
RXCUI
1546419
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY RxNorm
PUBCHEM
104729
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
DRUG BANK
DB14205
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
FDA UNII
AI1MR454XG
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
CHEBI
48828
Created by admin on Fri Dec 15 18:48:35 GMT 2023 , Edited by admin on Fri Dec 15 18:48:35 GMT 2023
PRIMARY
Related Record Type Details
Structure of COBALT DISODIUM EDETATE
SALT/SOLVATE -> PARENT
Structure of COBALT SUCCINATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS OXALATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS SULFIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS THIOCYANATE
SALT/SOLVATE -> PARENT
Structure of COBALT OXIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS GLUCONATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS NITRATE HEXAHYDRATE
SALT/SOLVATE -> PARENT
Structure of COBALT ACETYLMETHIONATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS CARBONATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS OXIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS PHOSPHATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS CHLORIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS NITRATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS OCTANOATE
SALT/SOLVATE -> PARENT
Structure of COBALAMIN
SALT/SOLVATE -> PARENT
Structure of COBALTOUS SULFATE
SALT/SOLVATE -> PARENT
Structure of COBALT TITANIUM OXIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS ACETATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS CHLORIDE HEXAHYDRATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS 2-NAPHTHENIC ACID
SALT/SOLVATE -> PARENT
Structure of COBALTOUS OLEATE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS ACETATE TETRAHYDRATE
SALT/SOLVATE -> PARENT
Structure of DICOBALT EDETATE
SALT/SOLVATE -> PARENT
Structure of COBALT ALUMINUM OXIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS BROMIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS LINOLEATE
SALT/SOLVATE -> PARENT
Structure of AMMONIUM COBALTOUS PHOSPHATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of COBALTOUS CATION
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