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Details

Stereochemistry ACHIRAL
Molecular Formula 3S.2Sb
Molecular Weight 339.715
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY TRISULFIDE

SMILES

[S--].[S--].[S--].[Sb+3].[Sb+3]

InChI

InChIKey=NVWBARWTDVQPJD-UHFFFAOYSA-N
InChI=1S/3S.2Sb/q3*-2;2*+3

HIDE SMILES / InChI
Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Sb
Molecular Weight 121.76
Charge 3
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Originator

Uhlenhuth, P.|Schmidt, H.
20

Approval Year

1921
1,467

Targets

Primary TargetPharmacologyConditionPotency
ATP-dependent 6-phosphofructokinase
21
Inhibitor
8,297

Conditions

ConditionModalityTargetsHighest PhaseProduct
Schistosomiasis
32
 Curative
Approved
8,429
Fuadin

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
F79059A38U
Record Status Validated (UNII)
Record Version
NIH
NCATS
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