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Details

Stereochemistry ACHIRAL
Molecular Formula Sb
Molecular Weight 121.7598
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 3

SHOW SMILES / InChI
Structure of ANTIMONY CATION (3+)

SMILES

[Sb+3]

InChI

InChIKey=FAWGZAFXDJGWBB-UHFFFAOYSA-N
InChI=1S/Sb/q+3

HIDE SMILES / InChI

Molecular Formula Sb
Molecular Weight 121.7598
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment:: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Conditions
PubMed

PubMed

TitleDatePubMed
Evaluation of fuadin therapy in schistosomiasis japonica.
1951 Apr
Laboratory studies on the joint effects of certain tris (p-aminophenyl) carbonium salts and antimonials as antischistosomal drugs.
1965
Current chemotherapy of schistosomiasis japonica in the Philippines.
1976 Jun
[Substantiation of maximum permissible levels of antimony trioxide and pentasulide in the atmospheric air of inhabitated places].
1989 Apr
Purification, kinetics and inhibition by antimonials of recombinant phosphofructokinase from Schistosoma mansoni.
1996 Oct 30
Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets.
2010 Jul 19
Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes.
2012 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 13:45:39 UTC 2021
Edited
by admin
on Sat Jun 26 13:45:39 UTC 2021
Record UNII
069647RPT5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY CATION (3+)
Common Name English
SB3 [WHO-DD]
Common Name English
ANTIMONY, ION (SB(3+))
Common Name English
ANTIMONY(3+)
Systematic Name English
SB3+
Common Name English
ANTIMONY CATION (3)
Common Name English
TRIVALENT ANTIMONY
Common Name English
Code System Code Type Description
FDA UNII
069647RPT5
Created by admin on Sat Jun 26 13:45:41 UTC 2021 , Edited by admin on Sat Jun 26 13:45:41 UTC 2021
PRIMARY
CAS
23713-48-6
Created by admin on Sat Jun 26 13:45:41 UTC 2021 , Edited by admin on Sat Jun 26 13:45:41 UTC 2021
PRIMARY
RXCUI
1546167
Created by admin on Sat Jun 26 13:45:41 UTC 2021 , Edited by admin on Sat Jun 26 13:45:41 UTC 2021
PRIMARY RxNorm
EPA CompTox
23713-48-6
Created by admin on Sat Jun 26 13:45:41 UTC 2021 , Edited by admin on Sat Jun 26 13:45:41 UTC 2021
PRIMARY
PUBCHEM
104894
Created by admin on Sat Jun 26 13:45:41 UTC 2021 , Edited by admin on Sat Jun 26 13:45:41 UTC 2021
PRIMARY
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