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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C4H2O6.2K.2Sb
Molecular Weight 613.827
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY POTASSIUM TARTRATE ANHYDROUS

SMILES

[K+].[K+].[Sb+3].[Sb+3].[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O.[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O

InChI

InChIKey=GUJUCWZGYWASLH-SOMOIXMJSA-J
InChI=1S/2C4H4O6.2K.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;/h2*1-2H,(H,7,8)(H,9,10);;;;/q2*-2;2*+1;2*+3/p-4/t2*1-,2-;;;;/m11..../s1

HIDE SMILES / InChI

Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H2O6
Molecular Weight 146.0551
Charge -4
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Sb
Molecular Weight 121.76
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Conditions
PubMed

PubMed

TitleDatePubMed
Laboratory studies on the joint effects of certain tris (p-aminophenyl) carbonium salts and antimonials as antischistosomal drugs.
1965
Current chemotherapy of schistosomiasis japonica in the Philippines.
1976 Jun
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:14:54 GMT 2023
Edited
by admin
on Fri Dec 15 18:14:54 GMT 2023
Record UNII
Z8830U53UE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY POTASSIUM TARTRATE ANHYDROUS
Common Name English
DIPOTASSIUM BIS(.MU.-(L-(+)-TARTRATO(4-)))DIANTIMONATE(2-)
Common Name English
ANTIMONATE(2-), BIS(.MU.-(2,3-DIHYDROXYBUTANEDIOATO(4-)-O(SUP 1),O(SUP 2):O(SUP 3),O(SUP 4)))-DI-, DIPOTASSIUM, STEREOISOMER
Common Name English
Code System Code Type Description
PUBCHEM
76968156
Created by admin on Fri Dec 15 18:14:54 GMT 2023 , Edited by admin on Fri Dec 15 18:14:54 GMT 2023
PRIMARY
CAS
11071-15-1
Created by admin on Fri Dec 15 18:14:54 GMT 2023 , Edited by admin on Fri Dec 15 18:14:54 GMT 2023
PRIMARY
FDA UNII
Z8830U53UE
Created by admin on Fri Dec 15 18:14:54 GMT 2023 , Edited by admin on Fri Dec 15 18:14:54 GMT 2023
PRIMARY
ECHA (EC/EINECS)
234-293-3
Created by admin on Fri Dec 15 18:14:54 GMT 2023 , Edited by admin on Fri Dec 15 18:14:54 GMT 2023
PRIMARY
EPA CompTox
DTXSID60858781
Created by admin on Fri Dec 15 18:14:54 GMT 2023 , Edited by admin on Fri Dec 15 18:14:54 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY