ANTIMONY TRIIODIDE

US Previously Marketed

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	3I.Sb
Molecular Weight	502.473
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Sb+3].[I-].[I-].[I-]

InChI

InChIKey=KWQLUUQBTAXYCB-UHFFFAOYSA-K

InChI=1S/3HI.Sb/h3*1H;/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula	Sb
Molecular Weight	121.76
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	HI
Molecular Weight	127.9124
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.whocc.no/atcvet/atcvet_index/?code=QR05CA07https://www.ncbi.nlm.nih.gov/pubmed/5295139 | https://www.ncbi.nlm.nih.gov/pubmed/14851220 | https://www.ncbi.nlm.nih.gov/pubmed/8898332
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
ATP-dependent 6-phosphofructokinase 21 Target ID: Q27778 Gene ID: NA Gene Symbol: PFK Target Organism: Schistosoma mansoni (Blood fluke) Sources: https://www.ncbi.nlm.nih.gov/pubmed/8898332 \| https://www.ncbi.nlm.nih.gov/pubmed/13446367	Inhibitor 8146

Conditions

Condition	Modality	Targets	Highest Phase	Product
Schistosomiasis 32 Sources: https://www.ncbi.nlm.nih.gov/pubmed/193200 https://www.ncbi.nlm.nih.gov/pubmed/193201 https://www.ncbi.nlm.nih.gov/pubmed/13268811 https://www.ncbi.nlm.nih.gov/pubmed/20292219	Curative		Approved 8307	Fuadin Approved Use Schistosomiasis
Unknown 2554

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 16 18:59:51 UTC 2022` Edited by `admin` on `Fri Dec 16 18:59:51 UTC 2022`
Record UNII	52ZE5Y9Y82
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ANTIMONY TRIIODIDE

Systematic Name

English

ANTIMONIUM IODATUM

Common Name

English

ANTIMONY TRIIODIDE [MI]

Common Name

English

ANTIMONY(III) TRIIODIDE

Systematic Name

English

STIBINE, TRIIODO-

Systematic Name

English

ANTIMONY TRIIODIDE [HSDB]

Common Name

English

ANTIMONIUM IODATUM [HPUS]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C579