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Details

Stereochemistry ACHIRAL
Molecular Formula 3Cl.Sb
Molecular Weight 228.119
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY TRICHLORIDE

SMILES

[Cl-].[Cl-].[Cl-].[Sb+3]

InChI

InChIKey=FAPDDOBMIUGHIN-UHFFFAOYSA-K
InChI=1S/3ClH.Sb/h3*1H;/q;;;+3/p-3

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Sb
Molecular Weight 121.76
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Originator

Approval Year

1921
1447
Targets

Targets

Primary TargetPharmacologyConditionPotency
ATP-dependent 6-phosphofructokinase
21
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Inhibitor
8146
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8307
Fuadin

Approved Use

Schistosomiasis
PubMed

PubMed

TitleDatePubMed
Laboratory studies on the joint effects of certain tris (p-aminophenyl) carbonium salts and antimonials as antischistosomal drugs.
1965
[Substantiation of maximum permissible levels of antimony trioxide and pentasulide in the atmospheric air of inhabitated places].
1989 Apr
Patents

Patents

03976788
20
04062962
20
04197262
20
04562009
22
04596784
20
05025031
25
05463088
20
05656573
25
05776425
20
07713950
20
07737233
22
08268997
20
08354532
21
20080146527
20
20090076227
20
20090124802
20
7361689
20
7615300
20
US3085943
20
US3965016
20
US5232441
21

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 20:51:18 UTC 2022
Edited
by admin
on Fri Dec 16 20:51:18 UTC 2022
Record UNII
J281401KK3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY TRICHLORIDE
HSDB   MI  
Systematic Name English
ANTIMONY TRICHLORIDE [HSDB]
Common Name English
ANTIMONY TRICHLORIDE SOLUTION [MI]
Common Name English
ANTIMONY TRICHLORIDE (SB2CL6)
Common Name English
ANTIMONY TRICHLORIDE [MI]
Common Name English
ANTIMONY CHLORIDE (SBCL3)
Common Name English
ANTIMONY(III) CHLORIDE
Systematic Name English
ANTIMONY CHLORIDE (SB2CL6)
Common Name English
ANTIMONIUM MURIATICUM [HPUS]
Common Name English
ANTIMONIUM MURIATICUM
HPUS  
Common Name English
ANTIMONY (III) CHLORIDE
Systematic Name English
Code System Code Type Description
MESH
C054672
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
MERCK INDEX
M1966
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY Merck Index
EPA CompTox
DTXSID4044161
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
WIKIPEDIA
ANTIMONY TRICHLORIDE
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
HSDB
439
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
FDA UNII
J281401KK3
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
CAS
10025-91-9
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
CHEBI
74856
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
PUBCHEM
24814
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
ECHA (EC/EINECS)
233-047-2
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY
MERCK INDEX
M1966
Created by admin on Fri Dec 16 20:51:18 UTC 2022 , Edited by admin on Fri Dec 16 20:51:18 UTC 2022
PRIMARY Merck Index
Related Record Type Details
Structure of ANTIMONY CATION (3+)
PARENT -> SALT/SOLVATE
NIH
NCATS
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