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Details

Stereochemistry ACHIRAL
Molecular Formula Cl.O.Sb
Molecular Weight 173.212
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY CHLORIDE OXIDE

SMILES

[O--].[Cl-].[Sb+3]

InChI

InChIKey=LIRSFCJKZQBJRK-UHFFFAOYSA-M
InChI=1S/ClH.O.Sb/h1H;;/q;-2;+3/p-1

HIDE SMILES / InChI

Molecular Formula Sb
Molecular Weight 121.76
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Conditions
PubMed

PubMed

TitleDatePubMed
Evaluation of fuadin therapy in schistosomiasis japonica.
1951 Apr
Laboratory studies on the joint effects of certain tris (p-aminophenyl) carbonium salts and antimonials as antischistosomal drugs.
1965
Current chemotherapy of schistosomiasis japonica in the Philippines.
1976 Jun
[Substantiation of maximum permissible levels of antimony trioxide and pentasulide in the atmospheric air of inhabitated places].
1989 Apr
Purification, kinetics and inhibition by antimonials of recombinant phosphofructokinase from Schistosoma mansoni.
1996 Oct 30
Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets.
2010 Jul 19
Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes.
2012 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Thu Jul 06 01:52:41 UTC 2023
Edited
by admin
on Thu Jul 06 01:52:41 UTC 2023
Record UNII
Y7P96CY2ZK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY CHLORIDE OXIDE
MI  
Systematic Name English
STIBINE, CHLOROOXO-
Systematic Name English
ANTIMONY MONOCHLORIDE MONOOXIDE
Systematic Name English
POWDER OF ALGAROTH
Common Name English
C.I. 77055
Common Name English
ANTIMONY CHLORIDE (SBOCL)
Common Name English
CHLOROOXOSTIBINE (SBOCL)
Common Name English
CHLOROOXOANTIMONY
Systematic Name English
ANTIMONY OXYCHLORIDE
Systematic Name English
ANTIMONY CHLORIDE OXIDE [MI]
Common Name English
BASIC ANTIMONY CHLORIDE
Common Name English
MERCURIUS VITAE
Common Name English
CHLOROOXOSTIBINE
Systematic Name English
Code System Code Type Description
CAS
7791-08-4
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
PUBCHEM
9793982
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
FDA UNII
Y7P96CY2ZK
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
WIKIPEDIA
Antimony oxychloride
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
MERCK INDEX
M1954
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
232-238-8
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
EPA CompTox
DTXSID0064880
Created by admin on Thu Jul 06 01:52:41 UTC 2023 , Edited by admin on Thu Jul 06 01:52:41 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE