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Details

Stereochemistry ABSOLUTE
Molecular Formula 2C4H2O6.2K.2Sb.3H2O
Molecular Weight 667.873
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ANTIMONY POTASSIUM TARTRATE

SMILES

O.O.O.[K+].[K+].[Sb+3].[Sb+3].[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O.[O-][C@H]([C@@H]([O-])C([O-])=O)C([O-])=O

InChI

InChIKey=WBTCZEPSIIFINA-MSFWTACDSA-J
InChI=1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4/t2*1-,2-;;;;;;;/m11......./s1

HIDE SMILES / InChI

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H4O6
Molecular Weight 148.071
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Sb
Molecular Weight 121.76
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936

Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Q27778
Gene ID: NA
Gene Symbol: PFK
Target Organism: Schistosoma mansoni (Blood fluke)
Conditions
PubMed

PubMed

TitleDatePubMed
Evaluation of fuadin therapy in schistosomiasis japonica.
1951 Apr
Current chemotherapy of schistosomiasis japonica in the Philippines.
1976 Jun
[Substantiation of maximum permissible levels of antimony trioxide and pentasulide in the atmospheric air of inhabitated places].
1989 Apr
Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets.
2010 Jul 19
Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes.
2012 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:39:06 GMT 2023
Edited
by admin
on Fri Dec 15 15:39:06 GMT 2023
Record UNII
DL6OZ476V3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTIMONY POTASSIUM TARTRATE
HSDB   INCI   MART.   MI   USP   VANDF   WHO-DD  
INCI  
Official Name English
Antimony potassium tartrate [WHO-DD]
Common Name English
ANTIMONY POTASSIUM TARTRATE [USP MONOGRAPH]
Common Name English
DIPOTASSIUM BIS(.MU.-(L-(+)-TARTRATO(4-)))DIANTIMONATE(2-) TRIHYDRATE
Common Name English
ANTIMONATE(2-), BIS(.MU.-(2,3-DIHYDROXYBUTANEDIOATO(4-)-O(SUP 1),O(SUP 2):O(SUP 3),O(SUP 4)))-DI-, DIPOTASSIUM, TRIHYDRATE, STEREOISOMER
Common Name English
ANTIMONIUM TARTARICUM
HPUS  
Common Name English
ANTIMONIUM TARTARICUM [HPUS]
Common Name English
ANTIMONY POTASSIUM TARTRATE [VANDF]
Common Name English
ANTIMONY POTASSIUM TARTRATE [MART.]
Common Name English
ANTIMONY POTASSIUM TARTRATE [MI]
Common Name English
ANTIMONY POTASSIUM TARTRATE [HSDB]
Common Name English
ANTIMONY POTASSIUM TARTRATE [INCI]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C737
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
EPA PESTICIDE CODE 6201
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
Code System Code Type Description
WIKIPEDIA
ANTIMONY POTASSIUM TARTRATE
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
CAS
28300-74-5
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
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FDA UNII
DL6OZ476V3
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
MERCK INDEX
m1961
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY Merck Index
SMS_ID
100000077425
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
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NCI_THESAURUS
C76863
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
HSDB
1428
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
CHEBI
2761
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
RXCUI
981
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY RxNorm
EVMPD
SUB34747
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
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PUBCHEM
73415808
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PRIMARY
DRUG BANK
DB15587
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
EVMPD
SUB127075
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
ALTERNATIVE
EVMPD
SUB12916MIG
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
DAILYMED
DL6OZ476V3
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
MESH
D000966
Created by admin on Fri Dec 15 15:39:06 GMT 2023 , Edited by admin on Fri Dec 15 15:39:06 GMT 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY