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Details

Stereochemistry ACHIRAL
Molecular Formula Pb.S
Molecular Weight 239.3
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEAD SULFIDE

SMILES

[S--].[PbH2++]

InChI

InChIKey=DDCACOMLHWHRLN-UHFFFAOYSA-N
InChI=1S/Pb.S.2H/q+2;-2;;

HIDE SMILES / InChI
Molecular Formula Pb
Molecular Weight 207.2
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf

There is no information about biological and pharmacological application of lead sulfide. But is known, that sulfide of the lead is insoluble and a stable compound in the pH of blood and so one of the less toxic forms of lead. Chronic exposure may lead to the respiratory system toxicity, irritation of skin.

CNS Activity

CNS Active
3897
Curator's Comment: Lead iodide may damage the nervous system.

Approval Year

1921
1447
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
The effect of topical applications of lead fluoride on dental caries.
1947 Dec
The effect of topically applied fluorides on dental caries experience; report of findings with two, four and six applications of sodium fluoride and of lead fluoride.
1947 Oct 10
[Contribution to the study on allergy among workers exposed to lead oxide and lead sulfide].
1961 Jul-Dec
Microbial uptake of lead.
1972 Jun 23
Interaction of lead and bacterial lipids.
1975 May
Subacute effects of lead-oxide fumes in demolition workers.
1977 Jan 8
Abiotic factors affecting the toxicity of lead to fungi.
1979 Sep
Interconnection of activation volumes and activation enthalpies in cubic lead fluoride doped with alkali-metal cations.
1985 Jun 15
Lead oxide emissions--a case history.
1986
Mutagenic effects of lead (II) bromide.
1989 Dec
[The late effects of exposure to lead fluoride].
1992 Mar
Structural Chemistry of Poly(ethylene glycol) Complexes of Lead(II) Nitrate and Lead(II) Bromide.
1996 Nov 20
[Lead in the blood and protoporphyrin levels in erythrocytes in glass workers exposed to lead].
1997 Dec
Maternal low-level lead exposure reduces the expression of PSA-NCAM and the activity of sialyltransferase in the hippocampi of neonatal rat pups.
2008 Jul
The oxidative damage and inflammatory response induced by lead sulfide nanoparticles in rat lung.
2013 Oct
Autophagy plays a protective role in cell death of osteoblasts exposure to lead chloride.
2015 Dec 3
Probit analysis of comparative assays on toxicities of lead chloride and lead acetate to in vitro cultured human umbilical cord blood lymphocytes.
2015 Mar
Rat Testis Damage Caused by Lead Sulfide Nanoparticles After Oral Exposure.
2016 Mar
Highly luminescent nanoscale quasi-2D layered lead bromide perovskites with tunable emissions.
2016 Mar 11
Patents

Patents

04024183
8
04096267
7
04182764
6
04212711
6
04324768
6
04927548
6
07208133
6
08106070
6
08318767
7
20050200803
6
20060110313
6
20100004280
6
20120088788
6
6498249
6
6933402
6
7118830
6
7550586
6
US2366953
6
US2448516
6
US3431182
6
US3716424
6

Sample Use Guides

In Vivo Use Guide
Toxicity by Ingestion: Grade 2; LD50 = 0.5-5 g/kg.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 22:58:33 UTC 2022
Edited
by admin
on Fri Dec 16 22:58:33 UTC 2022
Record UNII
2425D15SYM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEAD SULFIDE
HSDB   MI  
Systematic Name English
LEAD(II) SULFIDE
Systematic Name English
LEAD SULFIDE [HSDB]
Common Name English
PLUMBOUS SULFIDE
Common Name English
LEAD SULFIDE (PBS)
Common Name English
LEAD SULFIDE [MI]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
215-246-6
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
DAILYMED
2425D15SYM
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
MESH
C018391
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
CAS
1314-87-0
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
EPA CompTox
DTXSID0025498
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
MERCK INDEX
M6746
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY Merck Index
WIKIPEDIA
LEAD(II) SULFIDE
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
FDA UNII
2425D15SYM
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
HSDB
639
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
RXCUI
1549104
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY RxNorm
PUBCHEM
9794739
Created by admin on Fri Dec 16 22:58:33 UTC 2022 , Edited by admin on Fri Dec 16 22:58:33 UTC 2022
PRIMARY
Related Record Type Details
Structure of HYDROGEN SULFIDE
PARENT -> SALT/SOLVATE
NIH
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