U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula S.Sn
Molecular Weight 150.775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STANNOUS SULFIDE

SMILES

[S--].[SnH2++]

InChI

InChIKey=HSYHHAXEGFEOLZ-UHFFFAOYSA-N
InChI=1S/S.Sn.2H/q-2;+2;;

HIDE SMILES / InChI

Molecular Formula Sn
Molecular Weight 118.71
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including: https://www.ncbi.nlm.nih.gov/pubmed/17645550 http://www.pharmacytimes.com/publications/issue/2014/august2014/r648_august2014 https://en.wikipedia.org/wiki/Tin(II)_fluoride

Readily soluble in water, SnF2 is hydrolysed. At low concentration, it forms species such as SnOH+, Sn(OH)2 and Sn(OH)3−. At higher concentrations, predominantly polynuclear species are formed, including Sn2(OH)22+ and Sn3(OH)42+. Aqueous solutions readily oxidise to form insoluble precipitates of SnIV, which are ineffective as a dental prophylactic. Tin(II) fluoride, commonly referred to commercially (with tin(II) in Latin) as stannous fluoride, is a chemical compound with the formula SnF2. It is a colorless solid used as an ingredient in toothpastes that are typically more expensive than those that use sodium fluoride. Stannous fluoride has both bactericidal and bacteriostatic properties, which fight plaque and treat/prevent gingivitis. The stannous fluoride also deposits a protective mineral barrier over exposed dentinal tubules to help prevent sensitivity pain from triggers such as hot or cold liquids and foods. Stannous fluoride is used under the trade name "Fluoristan" in the original formulation of the toothpaste Crest, though it was later replaced with sodium monofluorophosphate, or "Fluoristat". It is the active ingredient in Crest Pro Health brand toothpaste. Crest Pro Health issues a warning on the tube that stannous fluoride may cause staining, which can be avoided by proper brushing, and that its particular formulation is resistant to staining. Any stannous fluoride staining that occurs due to improper brushing is not permanent. Stannous fluoride is also used in Oral-B Pro-Expert. Stannous fluoride is also readily available in over-the-counter rinses.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
ULTRATAG RBC

Approved Use

Technetium Tc 99m-labeled red blood cells are used for blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding.
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Patents

Patents

Sample Use Guides

Unknown
Route of Administration: Dental
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:50:47 GMT 2023
Edited
by admin
on Fri Dec 15 19:50:47 GMT 2023
Record UNII
J4580W867H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
STANNOUS SULFIDE
MI  
Common Name English
STANNOUS SULFIDE [MI]
Common Name English
Code System Code Type Description
MERCK INDEX
m10188
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
215-248-7
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
EPA CompTox
DTXSID401014321
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
CAS
1314-95-0
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
FDA UNII
J4580W867H
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
WIKIPEDIA
Lead(II) sulfide
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
PUBCHEM
10130046
Created by admin on Fri Dec 15 19:50:48 GMT 2023 , Edited by admin on Fri Dec 15 19:50:48 GMT 2023
PRIMARY
Related Record Type Details
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PARENT -> SALT/SOLVATE