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Details

Stereochemistry ACHIRAL
Molecular Formula S.Sn
Molecular Weight 150.775
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of STANNOUS SULFIDE

SMILES

[S--].[SnH2++]

InChI

InChIKey=HSYHHAXEGFEOLZ-UHFFFAOYSA-N
InChI=1S/S.Sn.2H/q-2;+2;;

HIDE SMILES / InChI

Molecular Formula HS
Molecular Weight 33.073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Sn
Molecular Weight 118.71
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/olaflur.html | https://www.ncbi.nlm.nih.gov/pubmed/15528912 | https://clinicaltrials.gov/ct2/show/record/NCT00268138 | https://www.old.health.gov.il/units/pharmacy/trufot/alonim/4872.pdf

Olaflur (amine fluoride 297, trade name elmex gel) is a fluoride-containing substance that is an ingredient of toothpastes and solutions for the prevention of dental caries. Especially in combination with dectaflur, it is also used in the form of gels for the treatment of early stages of caries, sensitive teeth, and by dentists for the refluoridation of damaged tooth enamel. Olaflur is a salt consisting of an alkyl ammonium cation and fluoride as the counterion. With a long lipophilic hydrocarbon chain, the cation has surfactant properties. It forms a film layer on the surface of teeth, which facilitates incorporation of fluoride into the enamel. The top layers of the enamel's primary mineral, hydroxylapatite, are converted into the more robust fluorapatite. The fluoridation reaches only a depth of a few nanometres, which has raised doubts whether the mechanism really relies on the formation of fluorapatite.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

toxicity in mice: LD50 = 888 mg/kg
Route of Administration: Intraperitoneal
Cytotoxicity study: it was explored the cytotoxicity of the coating agent, Oleylamine in two cell lines, human epidermal keratinocyte (HaCaT) and lung fibroblast (CRL-1490) cells, at surface coating agent concentrations of 3, 10, 30, and 100 μM. Two exposure time points, 2 h, and 24 h were employed for the study. Oleylamine, is highly toxic, leading to almost 100% cell death.
Substance Class Chemical
Created
by admin
on Sat Dec 17 03:49:57 UTC 2022
Edited
by admin
on Sat Dec 17 03:49:57 UTC 2022
Record UNII
J4580W867H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
STANNOUS SULFIDE
MI  
Common Name English
STANNOUS SULFIDE [MI]
Common Name English
Code System Code Type Description
MERCK INDEX
M10188
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY Merck Index
ECHA (EC/EINECS)
215-248-7
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
EPA CompTox
DTXSID401014321
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
CAS
1314-95-0
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
FDA UNII
J4580W867H
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
WIKIPEDIA
Lead(II) sulfide
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
PUBCHEM
10130046
Created by admin on Sat Dec 17 03:49:58 UTC 2022 , Edited by admin on Sat Dec 17 03:49:58 UTC 2022
PRIMARY
Related Record Type Details
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