MATE-2

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:57:17 GMT 2023` Edited by `admin` on `Sat Dec 16 10:57:17 GMT 2023`
Protein Type	TRANSPORTER
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	B46KUN2O9L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MATE-2

Common Name

English

MATE-2K

Common Name

English

SLC47A2

Common Name

English

HMATE-2K

Common Name

English

SOLUTE CARRIER FAMILY 47 MEMBER 2

Common Name

English

HMATE-2

Common Name

English

MATE2

Common Name

English

MULTIDRUG AND TOXIN EXTRUSION PROTEIN 2

Common Name

English

MATE2-K

Common Name

English

FLJ31196

Common Name

English

Classification Tree Code System Code

UCSF-FDA TRANSPORTAL

SLC47A2

Created by admin on Sat Dec 16 10:57:21 GMT 2023 , Edited by admin on Sat Dec 16 10:57:21 GMT 2023

Code System Code Type Description

WIKIPEDIA

SLC47A2

Created by admin on Sat Dec 16 10:57:21 GMT 2023 , Edited by admin on Sat Dec 16 10:57:21 GMT 2023

PRIMARY

FDA UNII

B46KUN2O9L

Created by admin on Sat Dec 16 10:57:21 GMT 2023 , Edited by admin on Sat Dec 16 10:57:21 GMT 2023

PRIMARY

UNIPROT

Q86VL8

Created by admin on Sat Dec 16 10:57:21 GMT 2023 , Edited by admin on Sat Dec 16 10:57:21 GMT 2023

PRIMARY

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Comments:

Rifamycin is an inhibitor of renal transporters organic anion transporter (OAT) 3, multidrug and toxin extrusion (MATE) 1, and MATE2-K transporters in vitro, however, based on systemic concentrations of rifamycin observed after administration of the recommended dose, clinically relevant inhibition of these transporters in vivo is unlikely.