RISDIPLAM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H23N7O
Molecular Weight	401.4643
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of RISDIPLAM

Structure Search

SMILES

CC1=CN2N=C(C=C(C)C2=N1)C3=CC(=O)N4C=C(C=CC4=N3)N5CCNC6(CC6)C5

InChI

InChIKey=ASKZRYGFUPSJPN-UHFFFAOYSA-N

InChI=1S/C22H23N7O/c1-14-9-18(26-29-11-15(2)24-21(14)29)17-10-20(30)28-12-16(3-4-19(28)25-17)27-8-7-23-22(13-27)5-6-22/h3-4,9-12,23H,5-8,13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C22H23N7O
Molecular Weight	401.4643
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:06:24 GMT 2023` Edited by `admin` on `Sat Dec 16 18:06:24 GMT 2023`
Record UNII	76RS4S2ET1
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RISDIPLAM

Official Name

English

RO-7034067

Code

English

RG-7916

Code

English

RO7034067

Code

English

RISDIPLAM [USAN]

Common Name

English

RG7916

Code

English

EVRYSDI

Brand Name

English

RISDIPLAM [JAN]

Common Name

English

Risdiplam [WHO-DD]

Common Name

English

RISDIPLAM [ORANGE BOOK]

Common Name

English

RISDIPLAM [MI]

Common Name

English

risdiplam [INN]

Common Name

English

(7-(4,7-DIAZASPIRO(2.5)OCTAN-7-YL)-2-(2,8-DIMETHYLIMIDAZO(1,2-B)PYRIDAZIN-6-YL)PYRIDO(1,2-A)PYRIMIDIN-4-ONE

Systematic Name

English

4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE, 7-(4,7-DIAZASPIRO(2.5)OCT-7-YL)-2-(2,8-DIMETHYLIMIDAZO(1,2-B)PYRIDAZIN-6-YL)-

Systematic Name

English

Classification Tree Code System Code

EU-Orphan Drug

EU/3/19/2145

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

FDA ORPHAN DRUG

548116

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

Code System Code Type Description

INN

10614

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

CAS

1825352-65-5

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

EVMPD

SUB193759

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

NCI_THESAURUS

C167001

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

DAILYMED

76RS4S2ET1

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

RXCUI

2390935

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

DRUG BANK

DB15305

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

USAN

FG-179

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

FDA UNII

76RS4S2ET1

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

SMS_ID

100000178153

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

WIKIPEDIA

Risdiplam

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

PUBCHEM

118513932

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

MERCK INDEX

m12240

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

EPA CompTox

DTXSID701109185

Created by admin on Sat Dec 16 18:06:26 GMT 2023 , Edited by admin on Sat Dec 16 18:06:26 GMT 2023

PRIMARY

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ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Volume of Distribution	PHARMACOKINETIC				AT STEADY-STATE