U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C21H24FN3O4
Molecular Weight 401.4322
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DX-619

SMILES

COc1c(ccc2c1n(cc(c2=O)C(=O)O)[C@]3([H])C[C@]3([H])F)N4CC[C@]([H])(C4)C5(CC5)N

InChI

InChIKey=ZLICIITZJTYKAQ-DIOULYMOSA-N
InChI=1S/C21H24FN3O4/c1-29-19-15(24-7-4-11(9-24)21(23)5-6-21)3-2-12-17(19)25(16-8-14(16)22)10-13(18(12)26)20(27)28/h2-3,10-11,14,16H,4-9,23H2,1H3,(H,27,28)/t11-,14+,16-/m1/s1

HIDE SMILES / InChI

Molecular Formula C21H24FN3O4
Molecular Weight 401.4322
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats.
2010 Oct 9
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Jun 25 22:44:14 UTC 2021
Edited
by admin
on Fri Jun 25 22:44:14 UTC 2021
Record UNII
H012AL9PN0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DX-619
Common Name English
3-QUINOLINECARBOXYLIC ACID, 7-((3R)-3-(1-AMINOCYCLOPROPYL)-1-PYRROLIDINYL)-1-((1R,2S)-2-FLUOROCYCLOPROPYL)-1,4-DIHYDRO-8-METHOXY-4-OXO-
Systematic Name English
Code System Code Type Description
FDA UNII
H012AL9PN0
Created by admin on Fri Jun 25 22:44:14 UTC 2021 , Edited by admin on Fri Jun 25 22:44:14 UTC 2021
PRIMARY
PUBCHEM
9865774
Created by admin on Fri Jun 25 22:44:14 UTC 2021 , Edited by admin on Fri Jun 25 22:44:14 UTC 2021
PRIMARY
CAS
431058-65-0
Created by admin on Fri Jun 25 22:44:14 UTC 2021 , Edited by admin on Fri Jun 25 22:44:14 UTC 2021
PRIMARY
Related Record Type Details
TRANSPORTER -> INHIBITOR
TRANSPORTER -> INHIBITOR
TRANSPORTER -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY