U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Mon Oct 21 19:54:49 UTC 2019
Edited
by admin
on Mon Oct 21 19:54:49 UTC 2019
Source Materials Class ORGANISM
Source Materials Type VIRUS
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species Human Immunodeficiency Virus Type 1
Author NONE
Part WHOLE
Record UNII
859A956UY8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Common Name English
HIV-1
Common Name English
Related Record Type Details
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An Fc-aglycosylated, non€“T-cell€“depleting and CD4-specific humanized IgG1 derived from the parent murine B4, which binds to discontinuous, conformational epitopes on the HIV-receptor complex, including CD4 domain 1, and competitively blocks HIV entry
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EC50
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Tipranavir (TPV) is a non-peptidic HIV-1 protease inhibitor that inhibits the virus-specific processing of the viral Gag and Gag-Pol polyproteins in HIV-1 infected cells, thus preventing formation of mature virions.
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