Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H13FN3O12P3S |
| Molecular Weight | 487.186 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC(=O)N(C=C1F)[C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2
InChI
InChIKey=WIEOLFZNMKSGEX-NTSWFWBYSA-N
InChI=1S/C8H13FN3O12P3S/c9-4-1-12(8(13)11-7(4)10)5-3-28-6(22-5)2-21-26(17,18)24-27(19,20)23-25(14,15)16/h1,5-6H,2-3H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16)/t5-,6+/m0/s1
| Molecular Formula | C8H13FN3O12P3S |
| Molecular Weight | 487.186 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:44:22 UTC 2023
by
admin
on
Sat Dec 16 14:44:22 UTC 2023
|
| Record UNII |
842MLG4LPF
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
842MLG4LPF
Created by
admin on Sat Dec 16 14:44:23 UTC 2023 , Edited by admin on Sat Dec 16 14:44:23 UTC 2023
|
PRIMARY | |||
|
469172
Created by
admin on Sat Dec 16 14:44:23 UTC 2023 , Edited by admin on Sat Dec 16 14:44:23 UTC 2023
|
PRIMARY | |||
|
145819-92-7
Created by
admin on Sat Dec 16 14:44:23 UTC 2023 , Edited by admin on Sat Dec 16 14:44:23 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
TARGET ORGANISM->INHIBITOR |
|
||
|
TARGET -> INHIBITOR |
Emtricitabine 5'-triphosphate inhibits the activity of the HIV-1 reverse transcriptase by competing with the natural substrate deoxycytidine 5'-triphosphate and by being incorporated into nascent viral DNA which results in chain termination.
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE ACTIVE |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
|
