Approval Year
Substance Class |
Structurally Diverse
Created
by
admin
on
Edited
Sat Jun 26 22:44:46 UTC 2021
by
admin
on
Sat Jun 26 22:44:46 UTC 2021
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Source Materials Class | ORGANISM |
Source Materials Type | VIRUS |
Source Materials Parent | |
Part | POLYMERASE |
Record UNII |
A3Z87NSO0U
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Record Status |
Validated (UNII)
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Record Version |
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-
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A3Z87NSO0U
Created by
admin on Sat Jun 26 22:44:47 UTC 2021 , Edited by admin on Sat Jun 26 22:44:47 UTC 2021
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PRIMARY |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET |
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INHIBITOR->TARGET ORGANISM |
Delavirdine has demonstrated an IC50 of 0.26 micromolar against recombinant reverse transcriptase; at 3 micromolar, it halted the spread of virus in MT-4 cells and blocked replication of primary HIV-1 isolates in peripheral blood lymphocytes, including zidovudine-resistant variants.
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |