Carbadox is a veterinary medicine, which was approved by FDA for the treatment of swine dysentery and bacterial swine enteritis. In 2016 the FDA announced its plans to withdraw the approval of Mecadox (carbadox) due to the concern that the drug may leave trace amounts of carcinogenic residue in pork that could pose a cancer risk to people, however, the drug is still marketing.

Dinitolmide (also known as zoalene) is a nitrobenzamide coccidiostat developed by Dow Company. The drug is approved by FDA for the prevention and control of coccidiosis in chickens and turkeys. Dinitolmide is hazardous for man as it may cause mutations. Thus the substance should be handle with extreme caution.

Dichlorvos is a synthetic organic chemical used as an insecticide. Dichlorvos does not occur naturally in the environment, but is manufactured by industry. Dichlorvos is sold under many trade names including Vapona®, Atgard®, Nuvan®, and Task®. It is also used as an insecticide for slow release on pest-strips for pest control in homes.  Dichlorvos is used as an anthelmintic (worming agent) for dogs, swine, and horses, as a botacide (agent that kills fly larvae) for horses, and in flea collars for dogs. In 1995, EPA proposed cancellation of dichlorvos for all home uses, and for many commercial and industrial uses.

Apramycin is a broad-spectrum aminocyclitol antibiotic produced by a strain of Streptomyces tenebrarius. It has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. Apramycin is registered for use in more than twenty countries in cattle, pigs and chickens. The drug exerts its antibacterial effect by inhibiting protein synthesis at the level of peptidyl translocation. It is mostly used for treating gastrointestinal infections. Apramycin is available in soluble powder and feed premix formulations.

Efrotomycin (ET) is an antibiotic obtained by the incubation of Nocardia lacamduranns, and composed of 4 components: Efrotomycin A1, Efrotomycin A2, Efrotomycin B1, and Efrotomycin B2. Although its antibacterial spectrum is narrow, ET has an antibacterial effect on part of the Grampositive bacteria and on treponema, and has a growth promoting effect on pigs etc. ET is a pure-grade antibiotic that was designated as a feed additive. Under the brand name Producil Efrotomycin was indicated for increased rate of weight gain when incorporated into complete swine feeds at 3.6 to 14.5 g/ton. This antibiotic is a potent inhibitor of bacterial protein synthesis by interfering with peptide transfer reactions associated with the elongation factor Tu.

Ethopabate is a veterinary drug used in the prophylaxis and treatment of coccidiosis in chickens. It is an arylamide containing one phenyl ring, belonging to monocyclic aromatics, is a very safe drug. It has anticoccidial activity especially against intestinal forms and lacks activity against E. tenella of caecal worms. This drug is a competitor of PABA for absorption by the parasite and interferes with folate synthesis. It has good activity against E. acervulina and some strains of E. maxima and E. brunette. It has been used only in combination with Amprolium first at 4 ppm and later at 40 ppm. This drug has peak activity on 4th day of cycle. Ethopabate is a component of marketed AMPROL PLUS (amprolium, ethopabate), indicated for use as an aid in the prevention of coccidiosis (1) in broiler chickens and (2) in replacement chickens where immunity to coccidiosis is not desired.

Nequinate is an aid in the prevention of coccidiosis caused by E. tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati.

Famphur is an insecticide and antihelmenthic. Famphur is approved in cattle as a pour-on (NADA 34-697; 21 CFR 524.900) and as medicated feed (NADA 34-266; 21 CFR 558.254). It is a component of the FDA-approved TRAMISOL X-TRA Combination Paste, used for the treatment of cattle infected with the following parasites: Stomach worms (Haemonchus, Trichostrongylus, Ostertagia), intestinal worms (Trichostrongylus, Cooperia, Nematodirus, Bunostomum, Oesophagostomum), lungworms (Dictyocaulus), cattle grubs (Hypoderma), biting lice (Bovicola), and sucking lice (Linognathus, Solenoptes). Famphur is a cholinesterase-inhibiting drug.

Coumaphos is an organophosphate insecticide used against ectoparasites. It was approved by FDA for the control of gastrointestinal roundworms in cattle (Purina brand name). It was also used in medicated feed against internal parasites (Ascaidia galli, Capilleria obsignata and Heterakis gallinarum) in layer chickens (Meldane brand name). However, coumaphos is highly toxic to birds. Sever acute toxicity and eventual death were caused in hens after they were given oral doses of 10mg/kg for 1-8 days.The oral LD50 for coumaphos is 3mg/kg in wildbirds, 29.4mg/kg in mallard ducks, 7.94mg/kg in pheasants and 14mg/kg in chicken. Due to its toxicity, coumaphos is no longer available as a drug.

Ivermectin is a broad-spectrum anti-parasite medication. It was first marketed under the name Stromectol® and used against worms (except tapeworms), but, in 2012, it was approved for the topical treatment of head lice infestations in patients 6 months of age and older, and marketed under the name Sklice™ as well. Ivermectin is mainly used in humans in the treatment of onchocerciasis but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, and enterobiasis). Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair the normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms. It is sold under brand names Heartgard, Sklice and Stromectol in the United States, Ivomec worldwide by Merial Animal Health, Mectizan in Canada by Merck, Iver-DT in Nepal by Alive Pharmaceutical and Ivexterm in Mexico by Valeant Pharmaceuticals International. In Southeast Asian countries, it is marketed by Delta Pharma Ltd. under the trade name Scabo 6.