NEQUINATE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H23NO4
Molecular Weight	365.4223
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC1=C(OCC2=CC=CC=C2)C=C3NC=C(C(=O)OC)C(=O)C3=C1

InChI

InChIKey=NNOPDLNHPOLRRE-UHFFFAOYSA-N

InChI=1S/C22H23NO4/c1-3-4-10-16-11-17-19(23-13-18(21(17)24)22(25)26-2)12-20(16)27-14-15-8-6-5-7-9-15/h5-9,11-13H,3-4,10,14H2,1-2H3,(H,23,24)

HIDE SMILES / InChI

Description
Sources: https://www.law.cornell.edu/cfr/text/21/558.365 | https://www.ncbi.nlm.nih.gov/pubmed/4766564| https://www.drugs.com/international/nequinate.html

Nequinate is an aid in the prevention of coccidiosis caused by E. tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Eimeria tenella 10 Target ID: CHEMBL612854 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2549593 \| https://www.ncbi.nlm.nih.gov/pubmed/4766564	Inhibitor 8297

Conditions

Condition	Modality	Targets	Highest Phase	Product
Coccidiosis 45 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4766564	Preventing		Approved 8429	Statyl Approved Use An aid in the prevention of coccidiosis caused by E. tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti, and E. mivati. in poultry.

PubMed

Title	Date	PubMed
In vitro cultivation of Cryptosporidium parvum and screening for anticryptosporidial drugs.	1990 Aug	2221857
Determination of methylbenzoquate in premixes and animal feeds using liquid chromatography with fluorescence detection.	2005 May-Jun	16001838

Patents

Sample Use Guides

In Vivo Use Guide

Chickens: Amount per ton. Nequinate, 18.16 grams (0.002 percent). Feed continuously as the sole ration; do not feed to chickens over 16 weeks of age.

Route of Administration: Oral

In Vitro Use Guide

M.E.D. (minimum effective dose) = 0.001 ppm

Name

Type

Language

NEQUINATE

Official Name

English

3-QUINOLINECARBOXYLIC ACID, 6-BUTYL-1,4-DIHYDRO-4-OXO-7-(PHENYLMETHOXY)-, METHYL ESTER

Systematic Name

English

nequinate [INN]

Common Name

English

ICI 55,052

Code

English

AY-20385

Code

English

NEQUINATE [MI]

Common Name

English

Methyl 7-(benzyloxy)-6-butyl-1,4-dihydro-4-oxo-3-quinolinecarboxylate

Systematic Name

English

AY-20,385

Code

English

NEQUINATE [USAN]

Common Name

English

NEQUINATE [GREEN BOOK]

Common Name

English

ICI-55052

Code

English

METHYL BENZOQUATE [MART.]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 558.365