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Restrict the search for
histamine
to a specific field?
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Dimaprit (S-[3-(N,N-dimethylamino)propyl]isothiourea) has been shown to be a highly specific histamine H2-receptor agonist.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
SKF-91488 is a noncompetitive inhibitor of histamine-N-methyltransferase. It modulates the effects of exogenous histamine and endogenously released histamine induced by antigen challenge on plasma extravasation in the airway in guinea pigs in vivo. SKF-91488 raised dose-dependently the pain threshold in rodent antinociception tests. Endogenous central histamine, after SKF 91488 treatment, via activation of H, receptors produces reversal of hypotension, with improvement in the survival rate at 2 h after treatment, in rats subjected to critical haemorrhagic hypovolaemia.
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
1-Methylhistamine also known as tele-methylhistamine can be found primarily in most biofluids, including cerebrospinal fluid (CSF), urine, feces, and blood, as well as in human bone marrow, brain, and mast cell tissues; it is involved in histidine metabolism. This endogenous compound can be a marker of the inflammatory bowel disease because during the development of the disease it concentration is enhanced. Besides, experiments on dogs have revealed, that 1-methylhistamine can be used as a marker of intestinal inflammation in chronic gastrointestinal disease.
