Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | 126.1133 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CC1=CNC=N1
InChI
InChIKey=PRJKNHOMHKJCEJ-UHFFFAOYSA-N
InChI=1S/C5H6N2O2/c8-5(9)1-4-2-6-3-7-4/h2-3H,1H2,(H,6,7)(H,8,9)
| Molecular Formula | C5H6N2O2 |
| Molecular Weight | 126.1133 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice. | 2009-03 |
|
| Characterizing metabolic inhibition using electrochemical enzyme/DNA biosensors. | 2009-01-15 |
|
| Postelicitation model of allergic contact dermatitis for predicting the efficacy of topical drugs. | 2009-01 |
|
| High-throughput phenotypic characterization of Pseudomonas aeruginosa membrane transport genes. | 2008-10-03 |
|
| Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. | 2007-11-29 |
|
| 5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists. | 2007-08-23 |
|
| Hair analysis of histamine and several metabolites in C3H/HeNCrj mice by ultra performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry (UPLC-ESI-TOF-MS): influence of hair cycle and age. | 2007-03 |
|
| OFF response of bullfrog cones is shaped by terminal ionotropic GABA receptors. | 2006-12-11 |
|
| A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis. | 2006-12-01 |
|
| Rapid determination of histamine and its metabolites in mice hair by ultra-performance liquid chromatography with time-of-flight mass spectrometry. | 2006-11-03 |
|
| High pH accelerates GABA deactivation on perch-rho1B receptors. | 2006-11-03 |
|
| An ionotropic GABA receptor with novel pharmacology at bullfrog cone photoreceptor terminals. | 2005-12-12 |
|
| Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation. | 2005-05-17 |
|
| Suppression of different phases of systemic contact hypersensitivity by urocanic acid oxidation products. | 2004-09-02 |
|
| Peripheral GABAB agonists stimulate gastric acid secretion in mice. | 2004-07 |
|
| Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists. | 2004-06-01 |
|
| Coordination sphere vibrations in copper(II), nickel(II) and cobalt(II) complexes with 4-imidazoleacetic acid; metal isotope, deuteration, and density functional study. | 2004-06 |
|
| Mutations of the 2' proline in the M2 domain of the human GABAC rho1 subunit alter agonist responses. | 2004-05 |
|
| Pharmacology of GABA(A) receptors exhibiting different levels of spontaneous activity. | 2003-08-22 |
|
| Medicinal chemistry and molecular pharmacology of GABA(C) receptors. | 2002-08 |
|
| Imidazoline receptors in the heart: characterization, distribution, and regulation. | 2002-06 |
|
| trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and (+/-)-trans-2-aminomethylcyclopropanecarboxylic acid ((+/-)-TAMP) can differentiate rat rho3 from human rho1 and rho2 recombinant GABA(C) receptors. | 2002-02 |
|
| Effects of central imidazolinergic and alpha2-adrenergic activation on water intake. | 2001-09 |
|
| Multireceptor GABAergic regulation of synaptic communication in amphibian retina. | 2001-01-01 |
|
| Presence and measurement of imidazoleacetic acid, a gamma-aminobutyric acid agonist, in rat brain and human cerebrospinal fluid. | 1989-04 |
|
| Simultaneous determination of imidazoleacetic acid and N tau- and N pi-methylimidazoleacetic acids in human urine by high-performance liquid chromatography with fluorescence detection. | 1987-04-24 |
|
| Presence and measurement of methylimidazoleacetic acids in brain and body fluids. | 1982-11-10 |
|
| Quantitative determination of 1,4-methyl-imidazoleacetic acid in urine by high performance liquid chromatography. | 1982-11 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:59:12 GMT 2025
by
admin
on
Mon Mar 31 19:59:12 GMT 2025
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| Record UNII |
IGZ30Z24EJ
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| Record Status |
Validated (UNII)
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| Record Version |
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60104
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IGZ30Z24EJ
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645-65-8
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16974
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DTXSID50214751
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96215
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