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Details

Stereochemistry ACHIRAL
Molecular Formula C6H11N3
Molecular Weight 125.1716
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-METHYLHISTAMINE

SMILES

CN1C=NC(CCN)=C1

InChI

InChIKey=FHQDWPCFSJMNCT-UHFFFAOYSA-N
InChI=1S/C6H11N3/c1-9-4-6(2-3-7)8-5-9/h4-5H,2-3,7H2,1H3

HIDE SMILES / InChI

Molecular Formula C6H11N3
Molecular Weight 125.1716
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

1-Methylhistamine also known as tele-methylhistamine can be found primarily in most biofluids, including cerebrospinal fluid (CSF), urine, feces, and blood, as well as in human bone marrow, brain, and mast cell tissues; it is involved in histidine metabolism. This endogenous compound can be a marker of the inflammatory bowel disease because during the development of the disease it concentration is enhanced. Besides, experiments on dogs have revealed, that 1-methylhistamine can be used as a marker of intestinal inflammation in chronic gastrointestinal disease.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown
Diagnostic
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
KCB81T4EOF
Record Status Validated (UNII)
Record Version