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Status:
Possibly Marketed Outside US
Source:
NEUROLITE by University of Montreal
Source URL:
First approved in 1994
Source:
NDA020256
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Bicisate hydrochloride is a ligand that is used to form a complex with technetium. Tc99m Bicisate forms a stable, lipophilic complex that crosses intact cell membranes and blood brain barrier by passive diffusion. The amount of tc99m bicisate is stable in the brain until about 6 hours. Tc99m bicisate is indicated as an adjunct to conventional CT or MRI imaging in the localization of stroke in patients in whom stroke has already been diagnosed.
Status:
Possibly Marketed Outside US
First approved in 1994
Source:
NADA141007
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Febantel is a anthelminthic agent used for the treatment of parasitic worms in animals.
Status:
First approved in 1994
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Status:
Possibly Marketed Outside US
Source:
KLEER-PLEX ADVANCED ACNE CARE SYSTEM
Source URL:
First approved in 1994
Source:
ANDA077538
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Phenethyl alcohol, or 2-phenylethanol, is an aromatic alcohol with a rosy scent. It is widely used in the food, fragrance, and cosmetic industries. It is used in the formulation of eye area makeup, skin care products, shampoos, perfumes, and colognes. Promising sources of natural 2-phenylethanol are microorganisms, especially yeasts, which can produce it by biosynthesis and biotransformation.
Status:
Possibly Marketed Outside US
Source:
CYHOT Cream with Lidocaine Well at WAlgreens
Source URL:
First approved in 1993
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Status:
Possibly Marketed Outside US
First approved in 1993
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Octisalate used as an ingredient in sunscreens and cosmetics. Maximum FDA-approved concentration - 5%. Range of protection - UVB. Might develop contact allergic dermatitis
Status:
Possibly Marketed Outside US
Source:
NICARB by McClary, C.F.
Source URL:
First approved in 1993
Source:
Nicarbazin by Phibro Animal Health Ltd
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Nicarbazin, a complex of two compounds, 4,4'-dinitrocarbanilide (DNC) and 4,6-dimethyl-2-pyrimidinol (HDP) is an effective drug for preventing intestinal and caecal coccidiosis in poultry. It is used for prevention rather than the treatment of disease. Nicarbazin was the first agent with “broad‐spectrum” activity against Eimeria spp. of chickens. Nicarbazin is used as a single agent or in combination with polyether antibiotics (narasin, or maduramicin), roxarsone, or antibiotics (lincomycin, bacitracin, flavomycin) for prevention and control of coccidiosis caused by Eimeria spp. (all relevant species) in broiler chickens. Nicarbazin can cause increased sensitivity to heat stress, which may result in growth depression and even mortality in broilers; death may be due to cell degeneration processes in liver and kidneys; at the recommended dose, the drug causes occasionally toxic effects in laying hens like reduced hatchability and interruption of egg-laying. Nicarbazin interferes with the formation of the vitelline membrane, separating the egg yolk and egg white. The exact mode of action is unknown, although it is thought nicarbazin interferes with cholesterol metabolism in the formation of the membrane.
Status:
Possibly Marketed Outside US
Source:
Unknown
Source URL:
First approved in 1993
Source:
21 CFR 352
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Dimethyl ether in combination with propane was approved to use in home conditions for the cryotherapy to treat warts. Nevertheless, this cold spray has to be used very careful not to damage unaffected areas of the skin.
Status:
Possibly Marketed Outside US
Source:
DEFENSIL-PLUS
Source URL:
First approved in 1993
Source:
21 CFR 333C
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Octyldodecanol is a long chain fatty alcohol. It is a medium spreading emollient which is due to its chemical structure hydrolysis stable and therefore beneficially suitable for all formulations where a wide pH range is needed e.g. deo/antiperspirant and hair remover formulations. It is an emulsifier and opacifying agent, used primarily as a thickener in moisturizers because of its lubricating and emollient properties in the formulation of skin care products. Octyldodecanol is approved by ECOCERT for Natural and Organic Cosmetics.
Status:
Possibly Marketed Outside US
First approved in 1993
Source:
NDA020215
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminum stearate is not classifiable as a human carcinogen (cancer-causing agent).