U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H6O
Molecular Weight 46.0684
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMETHYL ETHER

SMILES

COC

InChI

InChIKey=LCGLNKUTAGEVQW-UHFFFAOYSA-N
InChI=1S/C2H6O/c1-3-2/h1-2H3

HIDE SMILES / InChI
Dimethyl ether in combination with propane was approved to use in home conditions for the cryotherapy to treat warts. Nevertheless, this cold spray has to be used very careful not to damage unaffected areas of the skin.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Alcohols, ethers, carbohydrates, and related compounds. III. The 1,2-dimethoxyethane system.
2003-09
Hydrolysis kinetics of propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro.
2003-09
Biodegradation of potential diesel oxygenate additives: dibutyl maleate (DBM), and tripropylene glycol methyl ether (TGME).
2003-08
Cascade cyclizations via N,4-didehydro-2-(phenylamino)pyridine biradicals/zwitterions generated from enyne-carbodiimides.
2003-07-11
Controlled hydrophobic/hydrophilicity of chitosan for spheres without specific processing technique.
2003-07
Occupational exposure to glycol ethers and human congenital malformations.
2003-07
Tetramethylphosphonium fluoride: "naked" fluoride and phosphorane.
2003-05-05
The mechanism of methanol to hydrocarbon catalysis.
2003-05
Dual-level direct dynamics studies for the reactions of dimethyl ether with hydrogen atom and methyl radical.
2003-04-15
Human volunteer study with PGME: eye irritation during vapour exposure.
2003-04-11
A computational study of lithium enolate mixed aggregates.
2003-04-04
Palladium catalyzed kinetic and dynamic kinetic asymmetric transformations of gamma-acyloxybutenolides. Enantioselective total synthesis of (+)-Aflatoxin B1 and B2a.
2003-03-12
Propylene glycol monomethyl ether occupational exposure (PGME). 4. Analysis of 2-methoxypropionic acid in urine.
2003-03
Traceless liquid phase synthesis of piperazinediones.
2003-03
Significance of 2-methoxypropionic acid formed from beta-propylene glycol monomethyl ether: integration of pharmacokinetic and developmental toxicity assessments in rabbits.
2003-02
Exposure to ethylene glycol monomethyl ether: clinical and cytogenetic findings.
2003-01-18
Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice.
2003-01
Detection thresholds for phenyl ethyl alcohol using serial dilutions in different solvents.
2003-01
Metalloprotease-specific poly(ethylene glycol) methyl ether-peptide-doxorubicin conjugate for targeting anticancer drug delivery based on angiogenesis.
2003
Efficacy of two 65% permethrin spot-on formulations against induced infestations of Ctenocephalides felis (Insecta: Siphonaptera) and Amblyomma americanum (Acari: Ixodidae) on beagles.
2003
Stimulation of ligninolytic enzyme production in Phanerochaete chrysosporium by polyoxyalkanes.
2003
A computational study on addition of Grignard reagents to carbonyl compounds.
2002-12-27
Determination of docosahexaenoic acid and n-3 fatty acids in refined fish oils by 1H-NMR spectroscopy: IUPAC interlaboratory study.
2002-12-13
Sevoflurane anaesthesia in children after induction of anaesthesia with midazolam and thiopental does not cause epileptiform EEG.
2002-12
Fiber introduction mass spectrometry: fully direct coupling of solid-phase microextraction with mass spectrometry.
2002-11-01
Structures and aggregation states of fluoromethyllithium and chloromethyllithium carbenoids in the gas phase and in ethereal solvent.
2002-11-01
Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids.
2002-10-21
Functional group diversity in dendrimers.
2002-10-17
Energy efficient production of hydrogen and syngas from biomass: development of low-temperature catalytic process for cellulose gasification.
2002-10-15
Propylene glycol monomethyl ether (PGME): inhalation toxicity and carcinogenicity in Fischer 344 rats and B6C3F1 mice.
2002-10-10
Enzyme reaction engineering: effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions.
2002-10-05
Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether.
2002-10
Effects of experimental conditions on absorption of glycol ethers through human skin in vitro.
2002-10
Frequency effect on the sonochemical remediation of alachlor.
2002-10
An examination of the physical properties, fate, ecotoxicity and potential environmental risks for a series of propylene glycol ethers.
2002-10
Reactions of CH3OCH2+ with hydrocarbons and O, N, and S compounds: applications for chemical ionization in selected ion flow tube studies.
2002-09
Advantages of using non-isothermal bioreactors for the enzymatic synthesis of antibiotics: the penicillin G acylase as enzyme model.
2002-08-05
Two new minor polybrominated dibenzo-p-dioxins from the marine sponge Dysidea dendyi.
2002-08
Effect of endocrine disrupting chemicals on germinal vesicle breakdown in Xenopus in vitro.
2002-08
Maternal exposure to diethylene glycol monomethyl ether: a possible role in the etiology of retrocaval ureter.
2002-08
Recombinant squalene synthase. Synthesis of non-head-to-tail isoprenoids in the absence of NADPH.
2002-07-31
Molecular structures of cation...pi(arene) interactions for alkali metals with pi- and sigma-modalities.
2002-07-17
Ionic photodissociation in arylallyl acetates.
2002-07
Formation and decomposition of N,N,N-trimethylanilinium cations on zeolite H-Y investigated by in situ stopped-flow MAS NMR spectroscopy.
2002-06-26
Formal syntheses of heliannuols A and D, allelochemicals from Helianthus annus.
2002-03-21
Efficacy of two 65 % permethrin spot-on formulations against canine infestations of Ctenocephalides felis and Rhipicephalus sanguineus.
2002
Synthesis and analysis of a methyl ether derivative of tetracycline which inhibits growth of Escherichia coli.
2002
Lecithin microemulsions in dimethyl ether and propane for the generation of pharmaceutical aerosols containing polar solutes.
2002
Nanodosimetric measurements with an avalanche confinement TEPC.
2002
Chiral proton donor reagents: tin tetrachloride--coordinated optically active binaphthol derivatives.
2002
Patents
Name Type Language
DIMETHYL ETHER [HSDB]
Preferred Name English
DIMETHYL ETHER
HSDB   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
Dimethyl ether [WHO-DD]
Common Name English
DIMETHYL ETHER [MI]
Common Name English
1,1'-OXYBISMETHANE
Systematic Name English
DIMETHYL ETHER [VANDF]
Common Name English
METHYL ETHER
Systematic Name English
METHOXYMETHANE
Systematic Name English
DIMETHYL ETHER [MART.]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1737
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
Code System Code Type Description
MERCK INDEX
m4536
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY Merck Index
NCI_THESAURUS
C1645
Created by admin on Mon Mar 31 18:44:27 GMT 2025 , Edited by admin on Mon Mar 31 18:44:27 GMT 2025
PRIMARY
MESH
C033413
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
CAS
115-10-6
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PRIMARY
GRAS Notification (GRN No.)
695
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PRIMARY
GRAS Notification (GRN No.)
741
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
PUBCHEM
8254
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
FDA UNII
AM13FS69BX
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID8026937
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PRIMARY
EVMPD
SUB22907
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PRIMARY
RXCUI
1313349
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY RxNorm
WIKIPEDIA
DIMETHYL ETHER
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
HSDB
354
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
CHEBI
28887
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-065-8
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
DAILYMED
AM13FS69BX
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY
SMS_ID
100000088599
Created by admin on Mon Mar 31 18:44:28 GMT 2025 , Edited by admin on Mon Mar 31 18:44:28 GMT 2025
PRIMARY