U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2C18H35O2.Al.HO
Molecular Weight 610.9275
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALUMINUM DISTEARATE

SMILES

[OH-].[Al+3].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O

InChI

InChIKey=RDIVANOKKPKCTO-UHFFFAOYSA-K
InChI=1S/2C18H36O2.Al.H2O/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;;/h2*2-17H2,1H3,(H,19,20);;1H2/q;;+3;/p-3

HIDE SMILES / InChI
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H35O2
Molecular Weight 283.4693
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/25063173 | https://www.ncbi.nlm.nih.gov/pubmed/967230 | https://www.ncbi.nlm.nih.gov/pubmed/1234981 | https://www.ncbi.nlm.nih.gov/pubmed/374763

Because of its unusually heavy bodying properties, aluminum monostearate is used in the manufacture of paints, inks, greases, and waxes In recent years, hydrophobic aluminum monostearate was tested as a low-solubility denitrification substrate for anaerobic bacteria and a source of aluminum for phosphate precipitation. Aluminum monostearate can be used as a component of vehicle for delivery of drugs.

Approval Year

1993
136
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Approved
8429
Monoket

Approved Use

Monoket® is indicated for the prevention and treatment of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

Launch Date

1991
PubMed

PubMed

TitleDatePubMed
Serum concentrations following five treatment schedules with procaine penicillin in oil with aluminum monostearate.
1949 Feb
Results of single and multiple injection schedules for the treatment of early syphilis with procaine penicillin in oil and aluminum monostearate.
1950
"One shot" treatment of venereal diseases employing procaine penicillin G with aluminum monostearate (P. A. M.).
1950 Mar
Prolonged effect of riboflavin: aluminum monostearate suspensions in man.
1957 Feb
Long-acting narcotic antagonist complexes.
1975
Penicillin levels in blood and CSF achieved by treatment of syphilis.
1979 Jun 8
Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres.
2006 Feb 24
Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of Eudragit RS microspheres.
2006 Mar
Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy.
2012 Oct
Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system.
2014 Sep
Patents

Patents

04332814
3
04393223
3
04499288
3
04520014
3
05443698
3
US2032528
3
US3149036A
3
US4016273A
3

Sample Use Guides

In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:04:23 GMT 2023
Edited
by admin
on Fri Dec 15 15:04:23 GMT 2023
Record UNII
7P1HP1B9UI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALUMINUM DISTEARATE
HSDB   INCI  
INCI  
Official Name English
ALUMINIUM DISTEARATE
Systematic Name English
NSC-522176
Code English
ALUMINUM DISTEARATE [HSDB]
Common Name English
ALUMINUM DISTEARATE [INCI]
Common Name English
ALUMINIUM HYDROXIDE STEARATE
Systematic Name English
AL-ST 102
Common Name English
ALUMINUM, HYDROXYBIS(OCTADECANOATO-.KAPPA.O)-
Systematic Name English
ALUMINUM STEARATE 600
Common Name English
LIGASTER ALG-V
Common Name English
Classification Tree Code System Code
CFR 21 CFR 178.3297
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
Code System Code Type Description
CAS
300-92-5
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
SMS_ID
100000133528
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
ECHA (EC/EINECS)
206-101-8
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
EPA CompTox
DTXSID1027136
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
DAILYMED
7P1HP1B9UI
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
HSDB
5487
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
FDA UNII
7P1HP1B9UI
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
PUBCHEM
9315
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
NSC
522176
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
RXCUI
1307778
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY RxNorm
EVMPD
SUB51604
Created by admin on Fri Dec 15 15:04:23 GMT 2023 , Edited by admin on Fri Dec 15 15:04:23 GMT 2023
PRIMARY
Related Record Type Details
Structure of Stearic acid
PARENT -> SALT/SOLVATE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966