DIHEXADECYL PHOSPHATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C32H67O4P
Molecular Weight	546.8457
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCOP(O)(=O)OCCCCCCCCCCCCCCCC

InChI

InChIKey=RNPXCFINMKSQPQ-UHFFFAOYSA-N

InChI=1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

HIDE SMILES / InChI

Molecular Formula	C32H67O4P
Molecular Weight	546.8457
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: http://www.cir-safety.org/sites/default/files/alkpht022014SLR_0.pdf https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=ddab62ce-2527-4d0c-969c-738a805cf7cb&type=display	Palliative		Approved 8429	CYHOT Cream with Lidocaine Well at WAlgreens Approved Use Temporarily relieves pain and itching due to: • sunburn • minor burns • minor cuts • scrapes • insect bites Launch Date 2017

PubMed

Title	Date	PubMed
Structural analysis of the protein/lipid complexes associated with pore formation by the bacterial toxin pneumolysin.	2001 Feb 23	11076935
Effects of cholesterol and temperature on the permeability of dimyristoylphosphatidylcholine bilayers near the chain melting phase transition.	2001 Oct 1	11557016
Construction of stable anionic liposome-plasmid particles using the heating method: a preliminary investigation.	2002	12378277
Development of novel topical tranexamic acid liposome formulations.	2002 Mar 20	11879740
Physicochemical characterization of influenza viral vaccine loaded surfactant vesicles.	2003 Apr-Jun	12746052
A multi-wall carbon nanotubes-dicetyl phosphate electrode for the determination of hypoxanthine in fish.	2003 Sep	14516085
Ultrasound enhancement of drug release across non ionic surfactant vesicle membranes.	2004	17271051
Hydrophobic barrier in liposomes studied by FT-ESEEM.	2004 Feb	14979659
Interactions of complementary PEGylated liposomes and characterization of the resulting aggregates.	2004 Jul 20	15248699
Interaction of poly-L-arginine with dihexadecyl phosphate/phosphatidylcholine liposomes.	2005 Jun 21	15952852
Efficient drug delivery to atherosclerotic lesions and the antiatherosclerotic effect by dexamethasone incorporated into liposomes in atherogenic mice.	2005 May	16051539
ATP-dependent and drug-inhibited vesicle enlargement reconstituted using synthetic lipids and recombinant proteins.	2006	17379941
Modeling cell membrane transport: interaction of guanidinylated poly(propylene imine) dendrimers with a liposomal membrane consisting of phosphate-based lipids.	2006 Dec 19	17154621
Preparation of an ion-exchangeable polymer bead wrapped with bilayer membrane structures for high performance liquid chromatography.	2007 Apr 18	17397656
Comparative characterization of the physicochemical behavior and skin permeation of extruded DPPC liposomes modified by selected additives.	2007 Aug	17301964
Influence of a niosomal formulation on the oral bioavailability of acyclovir in rabbits.	2007 Dec 14	18181527
Skin permeation enhancement of ascorbyl palmitate by liposomal hydrogel (lipogel) formulation and electrical assistance.	2007 Feb	17268089
In vitro evaluation of enrofloxacin-loaded MLV liposomes.	2007 Jan	17107930
Fatty alcohols or fatty acids as niosomal hybrid carrier: effect on vesicle size, encapsulation efficiency and in vitro dye release.	2007 Jul 1	17339104
Study on the electrochemical behavior and differential pulse voltammetric determination of rhein using a nanoparticle composite film-modified electrode.	2007 May	16820331
Spontaneous vesicles of sodium dihexadecylphosphate in HEPES buffer.	2008 Apr 15	18295226
Spin labelling study of interfacial properties of egg-phosphatidylcholine liposomes as a function of cholesterol concentrations.	2008 Oct	18691564
Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes.	2008 Sep 1	18577437

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:59:10 GMT 2023` Edited by `admin` on `Sat Dec 16 19:59:10 GMT 2023`
Record UNII	2V6E5WN99N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIHEXADECYL PHOSPHATE

Systematic Name

English

DICETYL PHOSPHATE [INCI]

Common Name

English

NSC-12429

Code

English

DICETYL PHOSPHATE

Official Name

English

DICETYLPHOSPHATE

Systematic Name

English

Code System Code Type Description

CHEBI

60424