U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 46 results

Status:
US Approved Rx (1992)
First approved in 1972

Class (Stereo):
CHEMICAL (ABSOLUTE)


Desonide is a topical glucocorticoid which was approved by FDA for the treatment of such conditions as eczema, psoriasis, atopic dermatitis, etc. The exact mechanism of drug action is unknown.
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)


Clioquinol is a broad-spectrum antibacterial with antifungal properties, bacteriostatic. It is used as an antifungal and antiprotozoal topical drug OTC product for treatment of human infections. Previousely was used for wide number of intestinal diso...
Status:
US Approved Allergenic Extract (1994)
First approved in 1994

Class (Stereo):
CHEMICAL (ACHIRAL)



Nickel (II) oxide is an olive gray powder, insoluble in water and soluble in acids. It is produced industrially and used mainly as an intermediate in the production of nickel alloys and as a hydrogenation catalyst. Long-term inhalation of NiO is dama...
Status:
US Approved Allergenic Extract (1994)
First approved in 1960

Class (Stereo):
CHEMICAL (ACHIRAL)



Sodium 2-Mercaptobenzothiazole (sodium MBT) is utilized as a corrosion inhibitor and fungicide. By analogy to MBT, sodium MBT is identified as a skin sensitizer. Sodium 2-Mercaptobenzothiazole is also used to make rubber accelerators, as a preservati...
Status:
US Previously Marketed
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Pastaron (Urea) is a waste product of many living organisms, and is the major organic component of human urine. It is a very important starting material in a number of chemical syntheses, and is used on an industrial scale for the manufacture of fert...
Status:
Possibly Marketed Outside US
First approved in 2020

Class (Stereo):
CHEMICAL (RACEMIC)



Fulvic acid is primarily studied for its effects on plants and soil. Fulvic acid is an organic and natural electrolyte. Depending on the situation, Fulvic acid can act as an electron donor or acceptor and an oxidizer or reducer. Fulvic acid has exhib...
Status:
Possibly Marketed Outside US
First approved in 2018

Class (Stereo):
CHEMICAL (ABSOLUTE)



Riboflavin butyrate (a vitamin B2 derivative used widely in Japan) is often an ingredient of multivitamin complexes, used for relief of following symptoms: stomatitis, glossitis, perleche, cheilitis, rough skin, acne, dermatitis, eczema, rash, sores....
Status:
Possibly Marketed Outside US
First approved in 2000

Class (Stereo):
CHEMICAL (RACEMIC)


Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) exists as two distinct enantiomers: (2R) or D and (2S) or L. L-form is a metabolite in the glutathione cycle that is converted to glutamate by 5-ox...
Status:
Possibly Marketed Outside US
First approved in 1993

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Octyldodecanol is a long chain fatty alcohol. It is a medium spreading emollient which is due to its chemical structure hydrolysis stable and therefore beneficially suitable for all formulations where a wide pH range is needed e.g. deo/antiperspiran...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Bufexamac is a nonsteroidal antiinflammatory drug (NSAID) used in topical formulations to treat dermatological diseases (eczema and dermatitis) and proctological conditions (haemorrhoids and anal fissure). Bufexamac-containing medicines have been ava...