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Approval Year

Unknown
116683
Substance Class Protein
Created
by admin
on Sat Jun 26 18:04:25 UTC 2021
Edited
by admin
on Sat Jun 26 18:04:25 UTC 2021
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
V23K99CV7G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MUSCARINIC ACETYLCHOLINE RECEPTOR M1
Common Name English
CHRM1
Common Name English
Code System Code Type Description
PHAROS
P11229
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
FDA UNII
V23K99CV7G
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
UNIPROT
P11229
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
From To
1_98 1_178
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_2
N 1_12
Related Record Type Details
Structure of GLYCOPYRROLATE
INHIBITOR -> TARGET
Ki
Structure of TOLTERODINE
INHIBITOR -> TARGET
Structure of CYCLOPENTOLATE
INHIBITOR -> TARGET
Structure of SUCCINYLCHOLINE
AGONIST -> TARGET
Structure of TRIHEXYPHENIDYL
INHIBITOR -> TARGET
Structure of OXYBUTYNIN, (R)-
INHIBITOR -> TARGET
Structure of NERATINIB
INHIBITOR -> TARGET
Structure of ACLIDINIUM
ANTAGONIST->TARGET
Ki
Structure of THRX-195518
INHIBITOR -> TARGET
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
Structure of SOLIFENACIN
INHIBITOR -> TARGET
Ki
Structure of TAK-071
POSITIVE ALLOSTERIC MODULATOR->TARGET
Structure of PILOCARPINE
AGONIST -> TARGET
Structure of PALIPERIDONE
NON-INHIBITOR->OFF TARGET
NON-INHIBITOR
Ki
Structure of REVEFENACIN
INHIBITOR -> TARGET
BINDING
Kd
Structure of CARBACHOL
AGONIST -> TARGET
Structure of OXYBUTYNIN
INHIBITOR -> TARGET
Structure of NERATINIB
INHIBITOR->OFF-TARGET
DOXEPIN
INHIBITOR -> TARGET
Structure of 3-(2-(4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)-1-PIPERIDINYL)ETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO(1,2-A)PYRIMIDIN-4-ONE
OFF-TARGET->NON-INHIBITOR
Ki
Structure of ALVAMELINE
AGONIST -> TARGET
Structure of REVOSIMELINE
AGONIST -> TARGET
Structure of BLARCAMESINE
MODULATOR->TARGET
Structure of ATROPINE
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL
NIH
NCATS
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