U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 18:04:25 UTC 2021
Edited
by admin
on Sat Jun 26 18:04:25 UTC 2021
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
V23K99CV7G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MUSCARINIC ACETYLCHOLINE RECEPTOR M1
Common Name English
CHRM1
Common Name English
Code System Code Type Description
PHAROS
P11229
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
FDA UNII
V23K99CV7G
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
UNIPROT
P11229
Created by admin on Sat Jun 26 18:04:27 UTC 2021 , Edited by admin on Sat Jun 26 18:04:27 UTC 2021
PRIMARY
From To
1_98 1_178
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_2
N 1_12
Related Record Type Details
INHIBITOR -> TARGET
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
ANTAGONIST->TARGET
Ki
INHIBITOR -> TARGET
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
INHIBITOR -> TARGET
Ki
POSITIVE ALLOSTERIC MODULATOR->TARGET
AGONIST -> TARGET
NON-INHIBITOR->OFF TARGET
NON-INHIBITOR
Ki
INHIBITOR -> TARGET
BINDING
Kd
AGONIST -> TARGET
INHIBITOR -> TARGET
INHIBITOR->OFF-TARGET
INHIBITOR -> TARGET
OFF-TARGET->NON-INHIBITOR
Ki
AGONIST -> TARGET
AGONIST -> TARGET
MODULATOR->TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL