Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Thu Jul 06 17:22:55 UTC 2023
by
admin
on
Thu Jul 06 17:22:55 UTC 2023
|
| Protein Sub Type | |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
V23K99CV7G
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
P11229
Created by
admin on Thu Jul 06 17:22:57 UTC 2023 , Edited by admin on Thu Jul 06 17:22:57 UTC 2023
|
PRIMARY | |||
|
V23K99CV7G
Created by
admin on Thu Jul 06 17:22:57 UTC 2023 , Edited by admin on Thu Jul 06 17:22:57 UTC 2023
|
PRIMARY | |||
|
P11229
Created by
admin on Thu Jul 06 17:22:57 UTC 2023 , Edited by admin on Thu Jul 06 17:22:57 UTC 2023
|
PRIMARY |
| From | To |
|---|---|
| 1_98 | 1_178 |
| Glycosylation Type | HUMAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_2 |
| N | 1_12 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
AGONIST -> TARGET |
full agonist; pERK1/2
EC50
|
||
|
INHIBITOR -> TARGET |
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||
|
INHIBITOR -> TARGET |
Ki
|
||
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|
ACTIVATOR -> TARGET |
Promising, novel CNS-permeable oxime ACHE reactivator.
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||
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|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
Pirenzepine is a selective muscarinic M1 receptor
antagonist
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INHIBITOR -> TARGET | |||
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|
AGONIST -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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PARTIAL AGONIST->TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR->OFF-TARGET |
Radioligand binding assay
BINDING
IC50
|
||
|
ANTAGONIST->TARGET |
Ki
|
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|
INHIBITOR -> TARGET |
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
|
||
|
INHIBITOR -> TARGET |
Ki
|
||
|
POSITIVE ALLOSTERIC MODULATOR->TARGET | |||
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|
AGONIST -> TARGET | |||
|
NON-INHIBITOR->OFF TARGET |
NON-INHIBITOR
Ki
|
||
|
INHIBITOR -> TARGET |
BINDING
Kd
|
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|
AGONIST -> TARGET | |||
|
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INHIBITOR -> TARGET | |||
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INHIBITOR->OFF-TARGET |
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|
INHIBITOR -> TARGET |
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||
|
NON-INHIBITOR->OFF TARGET |
Ki
|
||
|
|
INHIBITOR -> TARGET |
Ki
|
||
|
AGONIST -> TARGET | |||
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|
AGONIST -> TARGET |
|
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|
MODULATOR->TARGET | |||
|
INHIBITOR -> TARGET |
|
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
|
||||
| MOL_WEIGHT | CHEMICAL |
|