Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 11:46:06 GMT 2023
by
admin
on
Sat Dec 16 11:46:06 GMT 2023
|
Protein Sub Type | |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
V23K99CV7G
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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P11229
Created by
admin on Sat Dec 16 11:46:08 GMT 2023 , Edited by admin on Sat Dec 16 11:46:08 GMT 2023
|
PRIMARY | |||
|
V23K99CV7G
Created by
admin on Sat Dec 16 11:46:08 GMT 2023 , Edited by admin on Sat Dec 16 11:46:08 GMT 2023
|
PRIMARY | |||
|
P11229
Created by
admin on Sat Dec 16 11:46:08 GMT 2023 , Edited by admin on Sat Dec 16 11:46:08 GMT 2023
|
PRIMARY |
From | To |
---|---|
1_98 | 1_178 |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
---|---|
N | 1_2 |
N | 1_12 |
Related Record | Type | Details | ||
---|---|---|---|---|
|
AGONIST -> TARGET |
full agonist; pERK1/2
EC50
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||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Ki
|
||
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AGONIST -> TARGET |
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||
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ACTIVATOR -> TARGET |
Promising, novel CNS-permeable oxime ACHE reactivator.
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||
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INHIBITOR -> TARGET |
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||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Pirenzepine is a selective muscarinic M1 receptor
antagonist
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||
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INHIBITOR -> TARGET | |||
|
RADIOLIGAND->TARGET |
Kd
|
||
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
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PARTIAL AGONIST->TARGET |
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
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INHIBITOR->OFF-TARGET |
Radioligand binding assay
BINDING
IC50
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||
|
INHIBITOR -> TARGET |
Ki
|
||
|
INHIBITOR -> TARGET |
Kd
|
||
|
INHIBITOR -> TARGET |
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
|
||
|
INHIBITOR -> TARGET |
Ki
|
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POSITIVE ALLOSTERIC MODULATOR->TARGET | |||
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AGONIST -> TARGET | |||
|
AGONIST -> TARGET |
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||
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NON-INHIBITOR->OFF TARGET |
NON-INHIBITOR
Ki
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AGONIST -> TARGET |
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INHIBITOR -> TARGET |
BINDING
Kd
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|
AGONIST -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR->OFF-TARGET |
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INHIBITOR -> TARGET |
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||
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PARTIAL AGONIST->TARGET |
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INHIBITOR -> TARGET |
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||
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NON-INHIBITOR->OFF TARGET |
Ki
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||
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INHIBITOR -> TARGET |
Ki
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PARTIAL AGONIST->TARGET |
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|
AGONIST -> TARGET |
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|
AGONIST -> TARGET |
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INHIBITOR -> TARGET |
BINDING
IC50
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MODULATOR->TARGET | |||
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INHIBITOR -> TARGET |
|
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
---|---|---|---|---|---|---|
Molecular Formula | CHEMICAL |
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||||
MOL_WEIGHT | CHEMICAL |
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