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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H31NO3
Molecular Weight 357.4864
Optical Activity ( - )
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Aroxybutynin

SMILES

CCN(CC)CC#CCOC(=O)[C@@](O)(C1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=XIQVNETUBQGFHX-QFIPXVFZSA-N
InChI=1S/C22H31NO3/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3/t22-/m0/s1

HIDE SMILES / InChI

Molecular Formula C22H31NO3
Molecular Weight 357.4864
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Preformulation studies on the S-isomer of oxybutynin hydrochloride, an Improved Chemical Entity (ICE).
2001 Apr
[Non-coordinated micturition syndrome mimicking posterior urethral valves in a male neonate].
2003 Jul
Acupressure versus oxybutinin in the treatment of enuresis.
2003 Nov-Dec
[Prevalence of urinary incontinence and linked factors in men and women over 65].
2003 Oct 15
Oxybutynin extended-release: a review of its use in the management of overactive bladder.
2004
Drug approval highlights for 2003.
2004 Feb
Rapid and selective UV spectrophotometric and RP-HPLC methods for dissolution studies of oxybutynin immediate-release and controlled-release formulations.
2004 Nov 15
A peripheric neuromodulation technique for curing detrusor overactivity: Stoller afferent neurostimulation.
2005
Prediction of genotoxicity of chemical compounds by statistical learning methods.
2005 Jun
Formulation and optimization of porous osmotic pump-based controlled release system of oxybutynin.
2007 Jul 13
The neurogenic bladder: medical treatment.
2008 May
Locked-in Syndrome in a Nigerian male with Multiple Sclerosis: a case report and literature review.
2008 Oct 30
Behavioral intervention versus pharmacotherapy or their combinations in the management of overactive bladder dysfunction.
2009
Oxybutynin extended release for the management of overactive bladder: a clinical review.
2009 Sep 21
Liquid Chromatographic Determination of Flavoxate HCl in Pharmaceutical Formulation.
2010 Jul
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 19:33:23 GMT 2023
Edited
by admin
on Sat Dec 16 19:33:23 GMT 2023
Record UNII
5BRQ29UUB7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Aroxybutynin
INN  
Official Name English
(-)-OXYBUTYNIN
Common Name English
OXYBUTYNIN, (-)-
Common Name English
4-(diethylamino)but-2-yn-1-yl (R)-cyclohexyl(hydroxy)(phenyl)acetate
Systematic Name English
(R)-OXYBUTYNIN
Common Name English
Benzeneacetic acid, α-cyclohexyl-α-hydroxy-, 4-(diethylamino)-2-butyn-1-yl ester, (αR)-
Systematic Name English
aroxybutynin [INN]
Common Name English
R-OXYBUTYNIN
Common Name English
OXYBUTYNIN, (R)-
Common Name English
Code System Code Type Description
FDA UNII
5BRQ29UUB7
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
CAS
119618-21-2
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
SMS_ID
300000045599
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
INN
12152
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
PUBCHEM
6098167
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
NCI_THESAURUS
C190351
Created by admin on Sat Dec 16 19:33:24 GMT 2023 , Edited by admin on Sat Dec 16 19:33:24 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
RACEMATE -> ACTIVE ENANTIOMER
TARGET -> INHIBITOR
ENANTIOMER -> ENANTIOMER
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY