MUSCARINIC ACETYLCHOLINE RECEPTOR M2

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:38:28 GMT 2023` Edited by `admin` on `Sat Dec 16 11:38:28 GMT 2023`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	U87RX375T5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MUSCARINIC ACETYLCHOLINE RECEPTOR M2

Common Name

English

acetylcholine receptor, muscarinic 2

Common Name

English

M2

Common Name

English

Code System Code Type Description

FDA UNII

U87RX375T5

Created by admin on Sat Dec 16 11:38:30 GMT 2023 , Edited by admin on Sat Dec 16 11:38:30 GMT 2023

PRIMARY

From	To
1_96	1_176
1_413	1_416

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_2
N	1_3
N	1_6
N	1_9

Related Record Type Details


					K9P6MC7092

INHIBITOR -> TARGET


					WHE7A56U7K

INHIBITOR -> TARGET


					NVJ76B897D

METHOCTRAMINE FREE BASE

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


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Amount:


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ATROPINE

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Qualification:

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Amount:


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INHIBITOR -> TARGET

Amount:


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Amount:


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Amount:


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Qualification:

Kd

Amount:


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Interaction Type:

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Qualification:

Kd

Amount:


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Comments:

methoctramine is a selective muscarinic M2 receptor antagonist

Amount:


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AF-DX-384

INHIBITOR -> TARGET

Qualification:

Kd

Amount:


					9ORI6L73CJ

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Amount:


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INHIBITOR -> TARGET

Qualification:

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Amount:


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AGONIST -> TARGET


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INHIBITOR -> TARGET

Amount:


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AGONIST -> TARGET

Amount:


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INHIBITOR->OFF-TARGET

Amount:


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NON-INHIBITOR->OFF TARGET

Interaction Type:

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Qualification:

Ki

Amount:


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INHIBITOR -> TARGET


					1IAT42T80T

INHIBITOR -> TARGET

Amount:


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ANTAGONIST->TARGET

Qualification:

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Amount:


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INHIBITOR -> TARGET

Amount:


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DOXEPIN

INHIBITOR -> TARGET

Amount:


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Amount:


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INHIBITOR -> TARGET

Comments:

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Interaction Type:

BINDING

Qualification:

Ki

Amount:


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WEAK INHIBITOR->TARGET

Qualification:

Ki

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL