{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
{{facet.count}}
Status:
Investigational
Source:
INN:fenacetinol [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Fenacetinol is an analgesic agent.
Class (Stereo):
CHEMICAL (RACEMIC)
Class (Stereo):
CHEMICAL (ACHIRAL)
Ponfibrate is clofibrate derivative. It is an antilipidemic agent with demonstrated hypobetalipoproteinemic effect.
Status:
Investigational
Source:
NCT00405119: Phase 2 Interventional Completed Gastroesophageal Reflux Disease
(2006)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
LAVOLTIDINE, also known as loxtidine, is a highly potent and selective histamine H2-receptor antagonist. It is a member of triazoles. It produces gastric carcinoid tumors in rodents that is why its clinical development was discontinued.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Bunolol is non-selective beta-adrenoreceptor antagonist with significant antihypertensive, antiarrhythmic and local anesthetic activities. Bunolol is a racemic mixture and Levobunolol is greater than 60 times more potent than its dextro isomer in its beta-blocking activity. Bunolol is 3 times as potent as propranolol by i.v. administration in anesthetized dogs in antagonizing the cardiovascular actions of isoproterenol and the response to cardioaccelerans nerve stimulation. When oral doses were given to unanesthetized dogs with subsequent induction of anesthesia, Bunolol was 20 times as potent as propranolol. The β-adrenergic blocking activity of Bunolol appeared to be competitive, and the activity was largely restricted to the l-isomer. Bunolol is extensively metabolized by both oxidative and reductive routes.
Class (Stereo):
CHEMICAL (ACHIRAL)
Isoxepac (also known) as HP-549 is a non-steroidal anti-inflammatory drug with analgesic activity. Isoxepac was studied in the clinical trial for the treatment of postoperative pain after knee surgery for meniscectomy. It was shown, that 200 mg of isoxepac would appear to be the minimal effective dose. In case of rheumatoid arthritis, isoxepac showed significantly fewer adverse effects.
Class (Stereo):
CHEMICAL (ABSOLUTE)
KALAFUNGIN is an antimicrobial agent obtained from the culture broth of a soil isolate of Streptomyces tanashiensis, designated Streptomyces tanashiensis strain Kala UC-5063. It has in vitro activity against a variety of pathogenic fungi, yeasts, protozoa, and bacteria.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Indoxole is phenylindene derivative patented by Mead Johnson & Co. as antidepressants. Indoxole have potent activity in the prevention of reserpine-induced ptosis in mice.
Class (Stereo):
CHEMICAL (ACHIRAL)
Fluradoline (also known as HP-494), a centrally acting antinociceptive agent with antidepressant properties. Experiments on rodents have shown that fluradoline blocked the reuptake of NE, 5-HT, and DA in the brain. Besides, fluradoline was studied for the prevention of acute and chronic postsurgical pain.
Status:
Investigational
Source:
INN:methiomeprazine [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)