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Details

Stereochemistry ACHIRAL
Molecular Formula C19H29N5O2
Molecular Weight 359.4659
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LAVOLTIDINE

SMILES

CN1N=C(CO)N=C1NCCCOC2=CC=CC(CN3CCCCC3)=C2

InChI

InChIKey=VTLNPNNUIJHJQB-UHFFFAOYSA-N
InChI=1S/C19H29N5O2/c1-23-19(21-18(15-25)22-23)20-9-6-12-26-17-8-5-7-16(13-17)14-24-10-3-2-4-11-24/h5,7-8,13,25H,2-4,6,9-12,14-15H2,1H3,(H,20,21,22)

HIDE SMILES / InChI

Molecular Formula C19H29N5O2
Molecular Weight 359.4659
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

LAVOLTIDINE, also known as loxtidine, is a highly potent and selective histamine H2-receptor antagonist. It is a member of triazoles. It produces gastric carcinoid tumors in rodents that is why its clinical development was discontinued.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
X16K5179V5
Record Status Validated (UNII)
Record Version