Kalafungin

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H12O6
Molecular Weight	300.2629
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H]1O[C@@H]2CC(=O)O[C@@H]2C3=C1C(=O)C4=C(C=CC=C4O)C3=O

InChI

InChIKey=XUWPJKDMEZSVTP-LTYMHZPRSA-N

InChI=1S/C16H12O6/c1-6-11-13(16-9(21-6)5-10(18)22-16)14(19)7-3-2-4-8(17)12(7)15(11)20/h2-4,6,9,16-17H,5H2,1H3/t6-,9-,16+/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5726156 | https://www.ncbi.nlm.nih.gov/pubmed/4303501

KALAFUNGIN is an antimicrobial agent obtained from the culture broth of a soil isolate of Streptomyces tanashiensis, designated Streptomyces tanashiensis strain Kala UC-5063. It has in vitro activity against a variety of pathogenic fungi, yeasts, protozoa, and bacteria.

Originator

Approval Year

PubMed

Title	Date	PubMed
Identification of HIV-1 integrase inhibitors based on a four-point pharmacophore.	1998-11	9865384
Kalafungin, a new antibiotic produced by Streptomyces tanashiensis strain Kala.	1968-12	5726156
Kalafungin, a new broad spectrum antibiotic. Isolation and characterization.	1968-07	4303501

Name

Type

Language

Kalafungin

Official Name

English

U-19718

Preferred Name

English

IBIOTIC PRODUCED BY STREPTOMYCES TANASHIENSIS STRAIN KALA. (1) 2H-FURO(3,2-B)NAPHTHO(2,3-D)PYRAN-2,6,11-TRIONE, 3,3A,5,11B-TETRAHYDRO-7-HYDROXY-5-METHYL-

Common Name

English

NSC-137443

Code

English

(+)-KALAFUNGIN

Common Name

English

kalafungin [INN]

Common Name

English

U-19,718

Code

English

KALAFUNGIN [USAN]

Common Name

English

Code System Code Type Description

SMS_ID

100000082865