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Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
ISOMOLPAN is a selective D3/D2 receptor agonist.
Status:
Investigational
Source:
INN:delequamine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Delequamine is a selective antagonist of alpha2 adrenoreceptor, developed by Syntex Research. The compound was investigated for the treatment of erectile dysfunction and was modestly effective in younger (less than 45 years) subjects.
Status:
Investigational
Source:
NCT00629694: Phase 2 Interventional Completed Otitis Media With Effusion
(2007)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Americium is a radioactive metallic element with atomic number 95 and element symbol Am. It's the only synthetic element encountered in everyday life, in minute quantities in ionization-type smoke detectors. Americium was first synthesized and identified in 1944 by Glenn T. Seaborg, Ralph James, L Morgan, and Albert Ghiorso at the University of California, Berkeley as part of the Manhattan Project. The element was produced using a 60-inch cyclotron. Americium is a shiny silver radioactive metal. All isotopes of this element are radioactive. The isotope with the longest half-life is americium-243, which has a half-life of 7370 years. The most common isotopes are americium-241, with a half-life of 432.7 years, and americium-243. Americium-242 is also known, with a half-life of 141 years. In total, 19 isotopes and 8 nuclear isomers have been characterized. The isotopes variously undergo alpha, beta, and gamma decay. EPA Facts AboutAmericium-241EPA Facts About Americium-241 July 2002 What is americium-241? Americium is a man-made radioactive metal that exists as a solid under normal conditions. Americium is produced when plutonium absorbs neutrons in nuclear reactors and nuclear weapons tests. Americium occurs in several forms called isotopes. The most common isotope is americium-241. Americium when blended with beryllium is used as a neutron source in the testing of machinery and in thickness gauges in the glass industry. Americium also is used as a radiation source in medical diagnostic devices and in research. Possible uses are in medicine where gamma emission of Am-241 has allowed the deter-mination of mineral content of bones, lipid content of soft tissues, and body composition. Americium is commonly used in minute amounts in smoke detectors as an ionization source. However this isotope is extremely expensive to produce in usable quantities. There is no known biological role of americium in living organisms. It's generally considered toxic because of its radioactivity.
Status:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Iodophthalein was used as an iodine-containing X-ray contrast agent in icteric subjects. There is also existed mention, that iodophthalein has also been used as a wound treatment, and for the treatment of intestinal catarrhs. But nowadays more modern drugs are being used.
Status:
Investigational
Source:
NCT01550484: Phase 2/Phase 3 Interventional Completed Parkinson's Disease
(2012)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
FLORBENAZINE F-18 is a fluorinated vesicular monoamine transporter type 2 (VMAT-2) ligand for positron-emission tomography. It has completed Phase II/III as a commercial radiopharmaceutical for the early detection and monitoring of neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, and dementia with Lewy bodies.
Status:
Investigational
Source:
INN:metallibure [INN]
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Methallibure is a non-steroidal gonadotropin antagonist. It affects monoamine metabolism. Methallibure suppresses pituitary, ovarian and renal function. Methallibure has been used in veterinary to control estrus synchronization.
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias
Class (Stereo):
CHEMICAL (ACHIRAL)
Demoxepam is a major pharmacologically active metabolite of the benzodiazepine chlordiazepoxide, the first drug within the class to gain approval by the Food and Drug Administration for use as an anticonvulsant, muscle relaxant and sedative hypnotic. Demoxepam has been shown to have antianxiety activity in man. The eventual elimination of demoxepam from the plasma was slow, with a range in half-life of 14-95 hr. The half-life of demoxepam was markedly longer than that of chlordiazepoxide. Demoxepam has an inhibitory effect on in vitro [3H]tryptophan binding to rat hepatic nuclei.
Status:
Investigational
Source:
NCT04523870: Not Applicable Interventional Completed Healthy
(2020)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT04421586: Not Applicable Interventional Completed Vaccination Uptake
(2020)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Fluquinconazole, a fungicide, that is approved under the name Jockey as a seed dressing in Australia.