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Details

Stereochemistry ACHIRAL
Molecular Formula C10H14O
Molecular Weight 150.2176
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SAFRANAL

SMILES

CC1=C(C=O)C(C)(C)CC=C1

InChI

InChIKey=SGAWOGXMMPSZPB-UHFFFAOYSA-N
InChI=1S/C10H14O/c1-8-5-4-6-10(2,3)9(8)7-11/h4-5,7H,6H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C10H14O
Molecular Weight 150.2176
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line.
2010-10
Sub-acute effects of diazinon on biochemical indices and specific biomarkers in rats: protective effects of crocin and safranal.
2010-10
Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus.
2010-10
Volatile composition screening of Salix spp. nectar honey: benzenecarboxylic acids, norisoprenoids, terpenes, and others.
2010-09
Extraction of crocin from saffron (Crocus sativus) using molecularly imprinted polymer solid-phase extraction.
2010-08
Crocus sativus L.: A comprehensive review.
2010-07
Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats.
2010-07
Effect of Crocus sativus L. (saffron) stigma and its constituents, crocin and safranal, on morphine withdrawal syndrome in mice.
2010-05
Effects of mild temperature conditions during dehydration procedures on saffron quality parameters.
2010-03-15
Self-modeling curve resolution techniques applied to comparative analysis of volatile components of Iranian saffron from different regions.
2010-03-10
Quantitative analysis of safranal in saffron extract and nanoparticle formulation by a validated high-performance thin-layer chromatographic method.
2009-10-29
Saffron is a monomorphic species as revealed by RAPD, ISSR and microsatellite analyses.
2009-09-23
Crocus sativus L. (Saffron) extract and its active constituents (crocin and safranal) on ischemia-reperfusion in rat skeletal muscle.
2009-09
Characterization of volatile components of Iranian saffron using factorial-based response surface modeling of ultrasonic extraction combined with gas chromatography-mass spectrometry analysis.
2009-08-14
An overview of structural features of DNA and RNA complexes with saffron compounds: Models and antioxidant activity.
2009-06-03
Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice.
2009-06
Metabolite and target transcript analyses during Crocus sativus stigma development.
2009-05
Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress.
2009-05
Cloning and functional characterization of carotenoid cleavage dioxygenase 4 genes.
2009
Interaction of safranal and picrocrocin with ctDNA and their preferential mechanisms of binding to GC- and AT-rich oligonucleotides.
2008-12
Stimulatory effect of Crocus sativus (saffron) on beta2-adrenoceptors of guinea pig tracheal chains.
2008-12
Effect of safranal on extracellular hippocampal levels of glutamate and aspartate during kainic Acid treatment in anesthetized rats.
2008-10
Self-help interventions for depressive disorders and depressive symptoms: a systematic review.
2008-08-19
Bacillus subtilis FZB24 affects flower quantity and quality of saffron (Crocus sativus).
2008-08
Quality and functionality of saffron: quality control, species assortment and affinity of extract and isolated saffron compounds to NMDA and sigma1 (sigma-1) receptors.
2008-06
The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats.
2008-06
Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography.
2008
Effect of safranal, a constituent of Crocus sativus (saffron), on methyl methanesulfonate (MMS)-induced DNA damage in mouse organs: an alkaline single-cell gel electrophoresis (comet) assay.
2007-12
An EST database from saffron stigmas.
2007-10-09
Interaction of tRNA with Safranal, Crocetin, and Dimethylcrocetin.
2007-06
Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: involvement of GABAergic and opioids systems.
2007-04
Inhibition of breast cancer cell proliferation by style constituents of different Crocus species.
2007-03-14
Crocetin, dimethylcrocetin, and safranal bind human serum albumin: stability and antioxidative properties.
2007-02-07
DNA interaction with saffron's secondary metabolites safranal, crocetin, and dimethylcrocetin.
2007-01
Microbial production of C13-norisoprenoids and other aroma compounds via carotenoid cleavage.
2007
A new approach to saffron aroma.
2007
Relaxant effect of Crocus sativus (saffron) on guinea-pig tracheal chains and its possible mechanisms.
2006-10
Determination of total safranal by in situ acid hydrolysis in supercritical fluid media: Application to the quality control of commercial saffron.
2006-09-25
Generation of saffron volatiles by thermal carotenoid degradation.
2006-09-06
Evaluation of the antitussive effect of stigma and petals of saffron (Crocus sativus) and its components, safranal and crocin in guinea pigs.
2006-09
Generation of aroma compounds from Ditaxis heterantha by Saccharomyces cerevisiae.
2006-08
Use of SPME-GC-MS in the study of time evolution of the constituents of saffron aroma: modifications of the composition during storage.
2006-01
Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice.
2005-12
Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents.
2005-11
Use of non-aqueous capillary electrophoresis for the quality control of commercial saffron samples.
2005-09-02
Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus.
2005-08-22
Effect of drying temperature and air flow on the production and retention of secondary metabolites in saffron.
2005-07-27
Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation.
2005-05
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial [ISRCTN45683816].
2004-09-02
Qualitative determination of volatile compounds and quantitative evaluation of safranal and 4-hydroxy-2,6,6-trimethyl-1-cyclohexene-1-carboxaldehyde (HTCC) in Greek saffron.
2004-07-14
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:31:26 GMT 2025
Edited
by admin
on Mon Mar 31 19:31:26 GMT 2025
Record UNII
4393FR07EA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,6,6-TRIMETHYLCYCLOHEXA-1,3-DIENYL METHANAL
FHFI  
Preferred Name English
SAFRANAL
MI  
Common Name English
1,1,3-TRIMETHYL-2-FORMYLCYCLOHEXA-2,4-DIENE
Systematic Name English
(2,6,6-TRIMETHYLCYCLOHEXA-1,3-DIENYL)METHANAL
Systematic Name English
2,3-DIHYDRO-2,2,6-TRIMETHYLBENZALDEHYDE
Systematic Name English
DEHYDRO-.BETA.-CYCLOCITRAL
Common Name English
2,6,6-TRIMETHYLCYCLOHEXA-1,3-DIENYL METHANAL [FHFI]
Common Name English
1,3-CYCLOHEXADIENE-1-CARBOXALDEHYDE, 2,6,6-TRIMETHYL-
Systematic Name English
2,6,6-TRIMETHYL-1,3-CYCLOHEXADIENAL
Systematic Name English
SAFRANAL [MI]
Common Name English
FEMA NO. 3389
Code English
2,6,6-TRIMETHYL-1,3-CYCLOHEXADIENE-1-CARBOXALDEHYDE
Systematic Name English
Classification Tree Code System Code
DSLD 2654 (Number of products:5)
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
Code System Code Type Description
CAS
116-26-7
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
MESH
C087963
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
JECFA MONOGRAPH
910
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
MERCK INDEX
m9722
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID7049398
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
WIKIPEDIA
SAFRANAL
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
PUBCHEM
61041
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
CHEBI
53169
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
FDA UNII
4393FR07EA
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-133-7
Created by admin on Mon Mar 31 19:31:26 GMT 2025 , Edited by admin on Mon Mar 31 19:31:26 GMT 2025
PRIMARY