DELEQUAMINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H26N2O3S
Molecular Weight	350.476
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C2[C@@H]3C[C@H]4[C@H](CCCN4S(C)(=O)=O)CN3CCC2=C1

InChI

InChIKey=JKDBLHWERQWYKF-JLSDUUJJSA-N

InChI=1S/C18H26N2O3S/c1-23-15-5-6-16-13(10-15)7-9-19-12-14-4-3-8-20(24(2,21)22)17(14)11-18(16)19/h5-6,10,14,17-18H,3-4,7-9,11-12H2,1-2H3/t14-,17+,18+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C18H26N2O3S
Molecular Weight	350.476
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2570150 | https://www.ncbi.nlm.nih.gov/pubmed/7871091

Delequamine is a selective antagonist of alpha2 adrenoreceptor, developed by Syntex Research. The compound was investigated for the treatment of erectile dysfunction and was modestly effective in younger (less than 45 years) subjects.

Approval Year

PubMed

Title	Date	PubMed
The alpha 2-adrenoceptor antagonist idazoxan reverses catalepsy induced by haloperidol in rats independent of striatal dopamine release: role of serotonergic mechanisms.	2003-05	12644843

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:32:35 GMT 2025` Edited by `admin` on `Mon Mar 31 19:32:35 GMT 2025`
Record UNII	L37HF85G8S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

(8AR,12AS,13AS)-5,8,8A,9,10,11,12,12A,13,13A-DECAHYDRO-3-METHOXY-12-(METHYLSULFONYL)-6H-ISOQUINO(2,1-G)(1,6)NAPHTHYRIDINE

Preferred Name

English

DELEQUAMINE

Official Name

English

delequamine [INN]

Common Name

English

Delequamine [WHO-DD]

Common Name

English

Code System Code Type Description

PUBCHEM

60713