DEXSOTALOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H20N2O3S
Molecular Weight	272.364
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)NC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1

InChI

InChIKey=ZBMZVLHSJCTVON-GFCCVEGCSA-N

InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3/t12-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C12H20N2O3S
Molecular Weight	272.364
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10917072

Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Arrhythmia 38 Sources: http://adisinsight.springer.com/drugs/800002184	Primary		Withdrawn	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.	2003 Oct	14594348

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:02:53 GMT 2023` Edited by `admin` on `Fri Dec 15 19:02:53 GMT 2023`
Record UNII	HO7QAP3XEF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DEXSOTALOL

Official Name

English

SOTALOL, (S)-

Common Name

English

Dexsotalol [WHO-DD]

Common Name

English

METHANESULFONAMIDE, N-(4-(1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, (S)-

Common Name

English

dexsotalol [INN]

Common Name

English

SOTALOL, D-

Common Name

English

D-SOTALOL

Common Name

English

N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)METHANESULFONAMIDE

Systematic Name

English

(S)-SOTALOL

Common Name

English

METHANESULFONANILIDE, 4'-(1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL)-, (+)-

Systematic Name

English

(+)-SOTALOL

Common Name

English

L-SOTALOL

Common Name

English

METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-

Systematic Name

English

Code System Code Type Description

ChEMBL

CHEMBL252312