DEXSOTALOL HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C12H20N2O3S.ClH
Molecular Weight	308.825
Optical Activity	( + )
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(C)NC[C@@H](O)C1=CC=C(NS(C)(=O)=O)C=C1

InChI

InChIKey=VIDRYROWYFWGSY-UTONKHPSSA-N

InChI=1S/C12H20N2O3S.ClH/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17;/h4-7,9,12-15H,8H2,1-3H3;1H/t12-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C12H20N2O3S
Molecular Weight	272.364
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/10917072

Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Arrhythmia 38 Sources: http://adisinsight.springer.com/drugs/800002184	Primary		Withdrawn	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
New antiarrhythmic agents for atrial fibrillation and atrial flutter: United States drug market response as an indicator of acceptance.	2003 Oct	14594348

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:33 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:33 GMT 2023`
Record UNII	2328OK6Q6P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DEXSOTALOL HYDROCHLORIDE

Official Name

English

(+)-(S)-4'-(1-HYDROXY-2-(ISOPROPYLAMINO)ETHYL)METHANESULFONANILIDE MONOHYDROCHLORIDE

Systematic Name

English

DEXSOTALOL HYDROCHLORIDE [USAN]

Common Name

English

BMY-05763-1-D

Code

English

(+)-SOTALOL HYDROCHLORIDE

Common Name

English

D-SOTALOL HYDROCHLORIDE

Common Name

English

(+)-MJ 1999

Code

English

SOTALOL HYDROCHLORIDE, D-

Common Name

English

BMY-05763-1D

Code

English

(+)-4'-(2-ISOPROPYLAMINO-1-HYDROXYETHYL)METHANESULFONANILIDE HYDROCHLORIDE

Common Name

English

METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, MONOHYDROCHLORIDE

Common Name

English

SOTALOL HYDROCHLORIDE, (S)-

Common Name

English

METHANESULFONAMIDE, N-(4-((1S)-1-HYDROXY-2-((1-METHYLETHYL)AMINO)ETHYL)PHENYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Dexsotalol hydrochloride [WHO-DD]

Common Name

English

Code System Code Type Description

USAN

GG-57