Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Glysobuzole (stabinol) is a sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glysobuzole is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Amelubant, its metabolite BIIL 260 (formed by removal of the ethoxycarbonyl protecting group), and its major metabolite BIIL 315 (formed by removal of the protecting group and glucuronidation) had potent in vitro and in vivo Leukotriene B4 receptor a...
Dexsotalol is an isomer of antiarrhythmic drug d,l-sotalol, but in opposite to drug, it increases the incidence of arrhythmias
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Ameltolide (ADD 75073, LY 201116) is a 4-aminobenzamide anticonvulsant patented by Research Corporation Technologies in the USA. Ameltolide is a sodium channel antagonist, it represents a potential therapy for the treatment of epilepsy. Ameltolide ha...
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Diclofensine is an antidepressant with equipotent inhibitive effects on the neuronal uptake of norepinephrine (NE), serotonin, and dopamine. It is devoid of monoamine-releasing or monoaminoxidase-inhibiting properties. Diclofensine was found to be an...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Lotrafiban (SmithKline Beecham) is a member of the latest generation of orally-active platelet GPIIb/IIIa blockers undergoing Phase III clinical trials to test the relative effectiveness versus other oral platelet inhibitors for ischaemic conditions ...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Isamoltan (CGP 361A) is a β-adrenoceptor and serotonin 1B receptor antagonist. Isamoltane has reported activity as an anxiolytic in man. Isamoltan had been in phase III clinical trials for the treatment of anxiety. However, this research has been dis...
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
RU 28318 also known as OXPRENOATE is a mineralocorticoid receptor (MR) antagonist, inhibiting aldosterone production and secretion. RU 28318 has been studied in normal and diabetic rats. It was revealed, that in combination with angiotensin convertin...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Etifenin is a diagnostic radiopharmaceutical for the liver function assessment. It is used for hepatobiliary function scintigraphy where there is the following suspicion: Acute cholecystitis; Chronic gall duct changes; Occlusion of ductus choledochus...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Methylbenactyzium bromide has been used as a spasmolytic for the
treatment of gastrointestinal ulcer and gastrointestinal spasms.