U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H17N3O3S2
Molecular Weight 327.422
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYSOBUZOLE

SMILES

COC1=CC=C(C=C1)S(=O)(=O)NC2=NN=C(CC(C)C)S2

InChI

InChIKey=LZCBNYVJTNCPDR-UHFFFAOYSA-N
InChI=1S/C13H17N3O3S2/c1-9(2)8-12-14-15-13(20-12)16-21(17,18)11-6-4-10(19-3)5-7-11/h4-7,9H,8H2,1-3H3,(H,15,16)

HIDE SMILES / InChI
Glysobuzole (stabinol) is a sulfonamide derivative with antihyperglycemic activity. Like sulfonylureas, glysobuzole is able to lower blood glucose levels by increasing the release of insulin from pancreatic beta cells.

Approval Year

PubMed

PubMed

TitleDatePubMed
Preliminary observations on management of diabetes with "stabinol".
1960 Sep 24
Patents

Sample Use Guides

Diabetes patients were started on four tablets of 250 mg (1 g) of stabinol (given in a single dose in the morning).
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
GLYSOBUZOLE
INN   WHO-DD  
INN  
Official Name English
ISOBUZOLE
Common Name English
glysobuzole [INN]
Common Name English
Glysobuzole [WHO-DD]
Common Name English
BENZENESULFONAMIDE, 4-METHOXY-N-(5-(2-METHYLPROPYL)-1,3,4-THIADIAZOL-2-YL)-
Systematic Name English
8002 C. B.
Code English
STABINOL
Brand Name English
NSC-34014
Code English
N-(5-ISOBUTYL-1,3,4-THIADIAZOL-2-YL)-P-METHOXYBENZENESULFONAMIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29711
Created by admin on Sat Dec 16 16:58:56 GMT 2023 , Edited by admin on Sat Dec 16 16:58:56 GMT 2023
Code System Code Type Description
SMS_ID
100000084236
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PRIMARY
ChEMBL
CHEMBL1481457
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INN
1195
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NSC
34014
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CAS
3567-08-6
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WIKIPEDIA
Glysobuzole
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EPA CompTox
DTXSID0046276
Created by admin on Sat Dec 16 16:58:56 GMT 2023 , Edited by admin on Sat Dec 16 16:58:56 GMT 2023
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NCI_THESAURUS
C65813
Created by admin on Sat Dec 16 16:58:56 GMT 2023 , Edited by admin on Sat Dec 16 16:58:56 GMT 2023
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PUBCHEM
234310
Created by admin on Sat Dec 16 16:58:56 GMT 2023 , Edited by admin on Sat Dec 16 16:58:56 GMT 2023
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EVMPD
SUB07958MIG
Created by admin on Sat Dec 16 16:58:56 GMT 2023 , Edited by admin on Sat Dec 16 16:58:56 GMT 2023
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FDA UNII
887VHL8899
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