Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H21NO2 |
| Molecular Weight | 247.3327 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCN1CCC[C@@H]2[C@@H]1COC3=CC=C(O)C=C23
InChI
InChIKey=GSLWRDKYYIQKIM-JSGCOSHPSA-N
InChI=1S/C15H21NO2/c1-2-7-16-8-3-4-12-13-9-11(17)5-6-15(13)18-10-14(12)16/h5-6,9,12,14,17H,2-4,7-8,10H2,1H3/t12-,14-/m0/s1
CNS Activity
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9539213
Curator's Comment: Known to be CNS active in rat. Human data not available.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors. | 2000-02-14 |
|
| Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release. | 1998-05 |
|
| Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways. | 1995-11 |
|
| Modulation of in vivo dopamine release by D2 but not D1 receptor agonists and antagonists. | 1987-03 |
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I06LXQ54TY
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107320-86-5
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100000082832
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)