ISOMOLPAN HYDROCHLORIDE

Cl.CCCN1CCC[C@H]2[C@H]1COC3=CC=C(O)C=C23

InChIKey=JFSZKRWNAVLJHH-QMDUSEKHSA-N

InChI=1S/C15H21NO2.ClH/c1-2-7-16-8-3-4-12-13-9-11(17)5-6-15(13)18-10-14(12)16;/h5-6,9,12,14,17H,2-4,7-8,10H2,1H3;1H/t12-,14-;/m1./s1

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

ISOMOLPAN is a selective D3/D2 receptor agonist.

PubMed

Title	Date	PubMed
Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors.	2000-02-14	10728880
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.	1998-05	9539213
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways.	1995-11	7473181
Modulation of in vivo dopamine release by D2 but not D1 receptor agonists and antagonists.	1987-03	2949060

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:12:03 GMT 2025` Edited by `admin` on `Mon Mar 31 18:12:03 GMT 2025`
Record UNII	REK7I52I58
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ISOMOLPAN HYDROCHLORIDE

Official Name

English

CGS-15855A

Preferred Name

English

Isomolpan hydrochloride [WHO-DD]

Common Name

English

CGS 15855A

Code

English

(±)-TRANS-1,3,4,4A,5,10B-HEXAHYDRO-4-PROPYL-2H-(1)BENZOPYRANO(3,4-B)PYRIDIN-9-OL HYDROCHLORIDE

Common Name

English

ISOMOLPAN HYDROCHLORIDE [USAN]

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2220428