A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 131. Liothyronine involves many important metabolic functions and is essential to the proper development and differentiation of all cells. I131 liothyronine may be used in radiotherapy in thyroid cancers.

Thyroxine I-125 is a radiolabeled thyroid hormone that has been used for diagnostics of thyroid disease. Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. Thyroxine plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones. A thyroxine test measures the level of Thyroxine in the plasma and Thyroxine I-125 was used as a radioiodine-labeled tracer for this assay. Currently Thyroxine I-125 primary use as a tracer for binding assays and other radiometric biological studies.

Androsterone, a neurosteroid, acts as a positive allosteric modulator of GABA(A) receptors, that can cross into the brain and could have effects on brain function. It was discovered, that the association of beta subunits with alpha subunits GABA(A) receptor affects the sensitivity of glycine receptors to androsterone. In spite of that, androsteron is considered as an inactive metabolite of testosterone. In addition, was studied that androsterone possessed anticonvulsant properties. Although of low potency, the androsterone was present in high abundance and was able to represent endogenous modulator of seizure susceptibility.

Quingestrone is a progestin, or a synthetic progestogen, patented by Laboratoires francais de chimiotherapie as an anti-inflammatory agent. Quingestrone acts as an agonist of the progesterone receptor weak glucocorticoid activity. Quingestrone was formerly used in combination with ethinylestradiol or mestranol in combined birth control pills in Italy. The medication was studied in the clinical prevention of miscarriage during pregnancy, but insufficient efficacy was observed at the dosage assessed

Thyropropic Acid (also known as Triopron) is a hydrocinnamic acid derivative and naturally occurring thyroid analog with antigoitrogenic and anticholesteremic activity. Thyropropic Acid acts as potent antagonist of thyroid hormone receptors and may be useful in the therapy of resistance to thyroid hormone and corticosteroid-induced skin atrophy. In preclinical models, Thyropropic Acid reduced serum cholesterol 27% and liver incorporation of acetate into cholesterol 37% but did not affect liver cholesterol levels.

Amcinafal is an anti-inflammatory agent. It is glucocorticoid corticosteroid.

A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 125. Liothyronine involves many important metabolic functions and is essential to the proper development and differentiation of all cells. I-125 liothyronine may be used in radiotherapy in thyroid cancers. It was used for the thyroxine T4 determination in serum by competitive protein-binding analysis.

The synthetic steroid nivazol lacks three of the substituents considered to be important for glucocorticoid activity, i.e. the 3-keto, the 11-hydroxy, and the 20-keto groups. Nevertheless, in the rat, nivazol has the activity profile of a glucocorticoid. Nivazol elicits numerous glucocorticoid activities in the rodent, but only the inhibition of the hypothalamic-pituitary-adrenal axis was observed in the primate. Nivazol has been investigated with respect to the treatment of Cushing's disease. In a patient with Nelson's syndrome nivazol was clearly highly effective in decreasing plasma ACTH concentrations and pigmentation. Its mechanism of action is similar to that of hydrocortisone. Both steroids directly inhibit in vitro ACTH secretion from corticotroph tumour cells removed from patients with Nelson's syndrome and block stimulation of ACTH release by ovine corticotrophin releasing factor and arginine vasopressin.

Epostane (WIN-32729) a pure competitive inhibitor of 3-beta-hydroxysteroid dehydrogenase. Epostane blocks progesterone synthesis during the luteal phase and in pregnancy in women and has strong anti-steroidogenic effect in endocrine tissues. Epostane is an abortifacient agent in early human pregnancy. It inhibits ovarian follicular steroidogenesis and ovulation.

Descinolone acetonide (an analog of triamcinolone acetonide) is a glucocorticoid which was developed for the treatment of skin disorders. It was tested on patients with psoriasis and atopic dermatitis, however there is no information about its further development.