LIOTHYRONINE I-125

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H12I3NO4
Molecular Weight	644.974
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CC1=CC([125I])=C(OC2=CC([125I])=C(O)C=C2)C([125I])=C1)C(O)=O

InChI

InChIKey=AUYYCJSJGJYCDS-QBYPCAMJSA-N

InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1/i16-2,17-2,18-2

HIDE SMILES / InChI

Molecular Formula	C15H12I3NO4
Molecular Weight	644.974
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=NCI_Thesaurus&code=C80096 | https://www.ncbi.nlm.nih.gov/pubmed/4990229

A radioconjugate of synthetic active thyroid hormone, liothyronine (T3), labeled with Iodine 125. Liothyronine involves many important metabolic functions and is essential to the proper development and differentiation of all cells. I-125 liothyronine may be used in radiotherapy in thyroid cancers. It was used for the thyroxine T4 determination in serum by competitive protein-binding analysis.

Approval Year

PubMed

Title	Date	PubMed
Serum thyroxine resin uptake of liothyronine I 125, and free thyroxine index.	1970-10	4990229

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:46:05 GMT 2025` Edited by `admin` on `Mon Mar 31 17:46:05 GMT 2025`
Record UNII	S1UAI9MKMG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LIOTHYRONINE I 125

Preferred Name

English

LIOTHYRONINE I-125

Common Name

English

L-TYROSINE, O-(4-HYDROXY-3-IODOPHENYL)-3,5-DIIODO-, LABELED WITH IODINE-125

Common Name

English

LIOTHYRONINE I 125 [USAN]

Common Name

English

LIOTHYRONINE (125I)

Common Name

English

L-ALANINE, 3-(4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL)-, LABELED WITH IODINE-125

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1446