THYROXINE I-125

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H11I4NO4
Molecular Weight	768.8706
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CC1=CC([125I])=C(OC2=CC([125I])=C(O)C([125I])=C2)C([125I])=C1)C(O)=O

InChI

InChIKey=XUIIKFGFIJCVMT-BNZZDVIVSA-N

InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1/i16-2,17-2,18-2,19-2

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4117902 | https://www.ncbi.nlm.nih.gov/pubmed/2483375 | https://www.ncbi.nlm.nih.gov/pubmed/24564653

Thyroxine I-125 is a radiolabeled thyroid hormone that has been used for diagnostics of thyroid disease. Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. Thyroxine plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones. A thyroxine test measures the level of Thyroxine in the plasma and Thyroxine I-125 was used as a radioiodine-labeled tracer for this assay. Currently Thyroxine I-125 primary use as a tracer for binding assays and other radiometric biological studies.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Comparative studies of I- 125 -T 3 , I- 125 -T 4 and I- 127 -PBI tests in thyroid diagnostics].	1972	4117902

Patents

Name

Type

Language

THYROXINE I-125

Common Name

English

L-TYROSINE, O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-, LABELED WITH IODINE-125

Common Name

English

THYROXINE-125I

Common Name

English

Thyroxine i 125 [WHO-DD]

Common Name

English

THYROXINE I 125 [USAN]

Common Name

English

THYROXINE, I-125

Common Name

English

THYROXINE I 125

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1553