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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H11I4NO4
Molecular Weight 768.8706
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THYROXINE I-125

SMILES

N[C@@H](CC1=CC([125I])=C(OC2=CC([125I])=C(O)C([125I])=C2)C([125I])=C1)C(O)=O

InChI

InChIKey=XUIIKFGFIJCVMT-BNZZDVIVSA-N
InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1/i16-2,17-2,18-2,19-2

HIDE SMILES / InChI
Thyroxine I-125 is a radiolabeled thyroid hormone that has been used for diagnostics of thyroid disease. Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. Thyroxine plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones. A thyroxine test measures the level of Thyroxine in the plasma and Thyroxine I-125 was used as a radioiodine-labeled tracer for this assay. Currently Thyroxine I-125 primary use as a tracer for binding assays and other radiometric biological studies.

Originator

Sources: Journal of the Korean Nuclear Society (1975), 7, (2), 127-33

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Name Type Language
THYROXINE I-125
Common Name English
L-TYROSINE, O-(4-HYDROXY-3,5-DIIODOPHENYL)-3,5-DIIODO-, LABELED WITH IODINE-125
Common Name English
THYROXINE-125I
Common Name English
Thyroxine i 125 [WHO-DD]
Common Name English
THYROXINE I 125 [USAN]
Common Name English
THYROXINE, I-125
Common Name English
THYROXINE I 125
USAN   WHO-DD  
USAN  
Official Name English
Classification Tree Code System Code
NCI_THESAURUS C1553
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
Code System Code Type Description
PUBCHEM
23725048
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
CAS
24486-40-6
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
CAS
24359-16-8
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
ALTERNATIVE
ChEMBL
CHEMBL42115
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
FDA UNII
7U4LEE5872
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
EVMPD
SUB15565MIG
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
SMS_ID
100000077009
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY
NCI_THESAURUS
C152595
Created by admin on Fri Dec 15 15:16:46 GMT 2023 , Edited by admin on Fri Dec 15 15:16:46 GMT 2023
PRIMARY